Gene Symbol | UBE2R2 |
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Entrez Gene | 54926 |
Alt Symbol | CDC34B, E2-CDC34B, UBC3B |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2R 2 |
Other Description | ubiquitin carrier protein R2|ubiquitin-conjugating enzyme E2 R2|ubiquitin-conjugating enzyme E2-CDC34B|ubiquitin-conjugating enzyme UBC3B|ubiquitin-protein ligase R2 |
Swissprots | D3DRL5 Q9NX64 Q712K3 |
Accessions | CCQ43572 EAW58478 EAW58479 EAW58480 Q712K3 AA397839 AJ240087 CAC80336 AK000426 BAA91156 AK225880 AL133827 AW966809 BC004862 AAH04862 BC038356 BC047584 AAH47584 BI061548 BI908167 BQ432410 CD515389 CN310827 CN427315 CR457233 CAG33514 XM_005251496 XP_005251553 XM_011517949 XP_011516251 NM_017811 NP_060281 |
Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin. {ECO:0000269|PubMed:12037680, ECO:0000269|PubMed:20061386}. |
Top Pathways | Ubiquitin mediated proteolysis, Herpes simplex infection |
Cdc34B CRISPR/Cas9 KO Plasmid (h) - sc-409280 from Santa Cruz Biotechnology
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Cdc34B HDR Plasmid (h) - sc-409280-HDR from Santa Cruz Biotechnology
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Cdc34B Double Nickase Plasmid (h) - sc-409280-NIC from Santa Cruz Biotechnology
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Cdc34B Double Nickase Plasmid (h2) - sc-409280-NIC-2 from Santa Cruz Biotechnology
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Cdc34B CRISPR Activation Plasmid (h) - sc-409280-ACT from Santa Cruz Biotechnology
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Cdc34B CRISPR Activation Plasmid (h2) - sc-409280-ACT-2 from Santa Cruz Biotechnology
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Cdc34B Lentiviral Activation Particles (h) - sc-409280-LAC from Santa Cruz Biotechnology
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Cdc34B Lentiviral Activation Particles (h2) - sc-409280-LAC-2 from Santa Cruz Biotechnology
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Cdc34B siRNA (h) - sc-105193 from Santa Cruz Biotechnology
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Cdc34B shRNA Plasmid (h) - sc-105193-SH from Santa Cruz Biotechnology
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Cdc34B shRNA (h) Lentiviral Particles - sc-105193-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU032611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22384 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22384 from Sigma-Aldrich
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UBE2R2 siRNA (Human) - CRJ0329 from Cohesion Biosciences
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UBE2R2 RNAi - H00054926-R01 from Novus Biologicals
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UBE2R2 - MBS8229422 from MyBioSource
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shRNA set against Human UBE2R2 (NM_017811.3) - SHH439164 from Creative biogene
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shRNA set against Human UBE2R2(NM_017811.3) - SHL111576 from Creative biogene
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UBE2R2 shRNA Plasmid (Human) - CHJ0329 from Cohesion Biosciences
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UBE2R2 miRNA 3'UTR clone - MiUTR1H-10957 from Creative biogene
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