Gene Symbol | LOXL3 |
---|---|
Entrez Gene | 84695 |
Alt Symbol | LOXL |
Species | Human |
Gene Type | protein-coding |
Description | lysyl oxidase-like 3 |
Other Description | lysyl oxidase homolog 3|lysyl oxidase-like protein 3 |
Swissprots | Q96RS1 Q6IPL7 D6W5J1 Q2EHP2 P58215 |
Accessions | AAX93223 CCQ43775 EAW99615 EAW99616 P58215 AF282619 AAK51671 AF284815 AAK91134 AF311313 AAK63205 AK309474 AK309478 BC033130 AAH33130 BC071865 AAH71865 DA554977 DQ378059 ABD23013 XM_011533134 XP_011531436 NM_001289164 NP_001276093 NM_001289165 NP_001276094 NM_032603 NP_115992 |
Function | Both isoforms function as amine oxidases toward elastin and different types of collagens. Isoform 1 shows the highest activity toward collagen type VIII, while Isoform 2 presents the highest activity toward collagen type IV. {ECO:0000269|PubMed:17018530}. |
Subcellular Location | Isoform 1: Secreted, extracellular space {ECO:0000305}. |
Tissue Specificity | Isoform 1 ia predominantly detected in the heart, placenta, lung, and small intestine, while isoform 2 is more highly detected in the kidney, pancreas, spleen, and thymus, and is absent in lung. {ECO:0000269|PubMed:17018530}. |
LOXL3 CRISPR/Cas9 KO Plasmid (h) - sc-402967 from Santa Cruz Biotechnology
|
||||||||
LOXL3 HDR Plasmid (h) - sc-402967-HDR from Santa Cruz Biotechnology
|
||||||||
LOXL3 Double Nickase Plasmid (h) - sc-402967-NIC from Santa Cruz Biotechnology
|
||||||||
LOXL3 Double Nickase Plasmid (h2) - sc-402967-NIC-2 from Santa Cruz Biotechnology
|
||||||||
LOXL3 CRISPR Activation Plasmid (h) - sc-402967-ACT from Santa Cruz Biotechnology
|
||||||||
LOXL3 CRISPR Activation Plasmid (h2) - sc-402967-ACT-2 from Santa Cruz Biotechnology
|
||||||||
LOXL3 Lentiviral Activation Particles (h) - sc-402967-LAC from Santa Cruz Biotechnology
|
||||||||
LOXL3 Lentiviral Activation Particles (h2) - sc-402967-LAC-2 from Santa Cruz Biotechnology
|
||||||||
LOXL3 siRNA (h) - sc-45224 from Santa Cruz Biotechnology
|
||||||||
LOXL3 shRNA Plasmid (h) - sc-45224-SH from Santa Cruz Biotechnology
|
||||||||
LOXL3 shRNA (h) Lentiviral Particles - sc-45224-V from Santa Cruz Biotechnology
|
||||||||
Lysyl Oxidase Homolog 3/LOXL3 RNAi - H00084695-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU052161 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN12639 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12639 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR07096 from Sigma-Aldrich
|
||||||||
LOXL3 siRNA (Human) - CRJ3588 from Cohesion Biosciences
|
||||||||
shRNA set against Human LOXL3 (NM_032603.2) - SHH333359 from Creative biogene
|
||||||||
shRNA set against Human LOXL3(NM_032603.2) - SHH159563 from Creative biogene
|
||||||||
LOXL3 shRNA Plasmid (Human) - CHJ3588 from Cohesion Biosciences
|
||||||||
LOXL3 miRNA 3'UTR clone - MiUTR1H-05878 from Creative biogene
|