MTA1

Gene Symbol	MTA1
Entrez Gene	9112
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	metastasis associated 1
Other Description	metastasis associated gene 1 protein|metastasis-associated protein MTA1
Swissprots	A5PLK4 Q96GI8 Q86SW2 Q8NFI8 Q13330
Accessions	EAW81918 EAW81919 EAW81920 EAW81921 EAW81922 EAW81923 Q13330 AB209348 BAD92585 AF508978 AAN01613 AW732089 BC006177 AAH06177 BC009443 AAH09443 BC142941 AAI42942 BE139515 BX248755 CAD66562 BX248776 CAD66583 DN997955 U35113 AAA78935 XM_011537301 XP_011535603 XM_011537302 XP_011535604 XM_011537303 XP_011535605 XM_011537304 XP_011535606 XM_011537305 XP_011535607 XM_011537306 XP_011535608 XM_011537307 XP_011535609 XM_011537308 XP_011535610 XM_011537309 XP_011535611 XM_011537310 XP_011535612 XM_011537311 XP_011535613 XM_011537312 XP_011535614 XM_011537313 XP_011535615 XM_011537314 XP_011535616 XM_011537315 XP_011535617 NM_001203258 NP_001190187 NM_004689 NP_004680
Function	Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. As a part of the histone-deacetylase multiprotein complex (NuRD), regulates transcription of its targets by modifying the acetylation status of the target chromatin and cofactor accessibility to the target DNA. In conjunction with other components of NuRD, acts as a transcriptional corepressor of BRCA1, ESR1, TFF1 and CDKN1A. Acts as a transcriptional coactivator of BCAS3, PAX5 and SUMO2, independent of the NuRD complex. Stimulates the expression of WNT1 by inhibiting the expression of its transcriptional corepressor SIX3. Plays a role in the inflammatory responses, both as a target and as a component of the NF-kappa-B signaling and regulates a subset of proinflammatory cytokines such as IL1B, MIP2, and TNF. Regulates p53-dependent and -independent DNA repair processes following genotoxic stress. Regulates the stability and function of p53/TP53 by inhibiting its ubiquitination by COP1 and M
Subcellular Location	Isoform Short: Cytoplasm.
Tissue Specificity	Widely expressed. High expression in brain, liver, kidney, and cardiac muscle, ovaries, adrenal glands and virgin mammary glands. Higher in tumors than in adjacent normal tissue from the same individual. Up-regulated in a wide variety of cancers including breast, liver, ovarian, and colorectal cancer and its expression levels are closely correlated with tumor aggressiveness and metastasis. {ECO:0000269|PubMed:16617102, ECO:0000269|PubMed:24970816}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MTA1 peptide - ab45449 from Abcam Category Peptide Species Human

MTA1 Antibody Blocking Peptide - LS-E25242 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MTA1 Antibody Blocking Peptide - LS-E13534 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MTA1 Antibody Blocking Peptide - LS-E13533 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MTA1 Partial Recombinant Protein - H00009112-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human MTA1 Protein - H00009112-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human MTA1 Protein - H00009112-Q03 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MTA1 blocking peptide - GTX20751-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

MTA1 Peptide - AC21-0069-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MTA1 - H00009112-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

MTA1 - H00009112-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MTA1 - H00009112-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MTA1 - H00009112-Q03-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MTA1 - H00009112-Q03-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MTA1 Peptide - 45-094P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

Recombinant Human MTA1, His-tagged - MTA1-29503TH from Creative Biomart Category Protein Source E. coli

Recombinant Metastasis Associated Protein 1 (MTA1) - RPC630Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

MTA1 (K182) Peptide - BS2045P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Metastasis-associated protein MTA1(MTA1) - CSB-YP619759HU CSB-EP619759HU CSB-BP619759HU CSB-MP619759HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MTA1 Blocking Peptide - abx161683 from Abbexa Category Peptide Species Human, Mouse, Rat

MTA1 - TP318599 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MTA1, Peptide - MBS425291 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

MTA1 Recombinant Protein Antigen - NBP1-89467PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MTA1-Blocking-PeptideC-term - BP19705B from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MTA1 Peptide, Human - M34GP09858H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more