Gene Symbol | LSS |
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Entrez Gene | 4047 |
Alt Symbol | OSC |
Species | Human |
Gene Type | protein-coding |
Description | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
Other Description | 2,3-epoxysqualene--lanosterol cyclase|2,3-epoxysqualene-lanosterol cyclase|hOSC|lanosterol synthase|oxidosqualene--lanosterol cyclase |
Swissprots | Q9UEZ1 Q8IYL6 G5E9Q9 B4DJZ9 D3DSN0 E9PEI9 P48449 |
Accessions | CAB42828 CAY34695 CBG17604 CBG17696 CBV30957 CBV31050 EAX09299 EAX09300 EAX09301 EAX09302 EAX09303 P48449 AA922470 AK092334 BAC03865 AK096769 BAC04859 AK098352 BAC05289 AK128839 BAC87638 AK226141 AK296313 BAG59011 AK312489 BAG35391 AY927524 BC035638 AAH35638 BM662957 BU728696 BX443698 D63807 BAA09875 DA333499 DQ891234 ABM82160 DQ894418 ABM85344 S81221 AAB36220 X87809 CAA61078 XM_006724004 XP_006724067 XM_011529564 XP_011527866 XM_011529565 XP_011527867 XM_011529566 XP_011527868 XM_011529567 XP_011527869 XR_937491 NM_001001438 NP_001001438 NM_001145436 NP_001138908 NM_001145437 NP_001138909 NM_002340 NP_002331 |
Function | Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. {ECO:0000269|PubMed:7639730}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:14766201, ECO:0000269|PubMed:15525992}; Peripheral membrane protein {ECO:0000269|PubMed:14766201, ECO:0000269|PubMed:15525992}. |
Top Pathways | Steroid biosynthesis |
Active Lysostaphin full length protein - ab70102 from Abcam
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Human LSS protein fragment - ab158831 from Abcam
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LSS Antibody Blocking Peptide - LS-E15394 from LifeSpan Bioscience
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LSS Antibody Blocking Peptide - LS-E15393 from LifeSpan Bioscience
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Recombinant Human LSS Protein - H00004047-Q01 from Novus Biologicals
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LSS-Antibody-C-term-Blocking-Peptide - BP9165b from Abgent, a WuXi AppTec company
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LSS-Antibody-N-term-Blocking-Peptide - BP9165a from Abgent, a WuXi AppTec company
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LSS Protein Lysate (APL10870) - APL10870 from Aviva Systems Biology
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LSS Blocking Peptide - 33R-9038 from Fitzgerald
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LSS Blocking Peptide - 33R-4275 from Fitzgerald
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Human Oxidosqualene Cyclase Protein - abx068410 from Abbexa
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Lanosterol synthase - H00004047-Q01-10 from Acris Antibodies
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Lanosterol synthase - H00004047-Q01-25 from Acris Antibodies
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Oxidosqualene Cyclase (OSC), Human - 20-8125 from ARP American Research Products
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LSS fusion protein - ag6955 from Proteintech Group
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LSS fusion protein - Ag4655 from Proteintech Group
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Recombinant Oxidosqualene Cyclase (OSC) - RPB898Hu01 from Uscn Life Science Inc.
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Recombinant Oxidosqualene Cyclase (OSC) - RPB898Hu02 from Uscn Life Science Inc.
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Recombinant Oxidosqualene Cyclase (OSC) - RPB898Ra01 from Uscn Life Science Inc.
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Recombinant Oxidosqualene Cyclase (OSC) - RPB898Hu01 from Cloud-clone
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Recombinant Oxidosqualene Cyclase (OSC) - RPB898Hu02 from Cloud-clone
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Recombinant Human Lanosterol synthase(LSS) - CSB-YP013216HU CSB-EP013216HU CSB-BP013216HU CSB-MP013216HU from Cusabio
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LSS Protein - abx164030 from Abbexa
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Lanosterol synthase (transcript variant 2) - TP314463 from Acris Antibodies
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LSS Recombinant Protein Antigen - NBP2-33966PEP from Novus Biologicals
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