| Gene Symbol |
ORMDL2
|
| Entrez Gene |
29095
|
| Alt Symbol |
HSPC160, MST095, MSTP095, adoplin-2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ORMDL sphingolipid biosynthesis regulator 2
|
| Other Description |
ORM1-like protein 2|expressed in normal aorta
|
| Swissprots |
B2RA58 Q8NFX0 Q7Z4E5 Q53FV1 Q9P004
|
| Accessions |
EAW96840 Q53FV1 AB064961 BAC11712 AF161509 AAF29124 AF173375 AAQ13618 AF395705 AAM43504 AF395706 AAM43505 AF395707 AAM43506 AK223180 BAD96900 AK314046 BAG36755 AW339474 BC012543 AAH12543 BG750383 EU831753 ACE87271 EU831830 ACE86589 NM_014182 NP_054901
|
| Function |
Negative regulator of sphingolipid synthesis. {ECO:0000269|PubMed:20182505}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:12093374}; Multi-pass membrane protein {ECO:0000269|PubMed:12093374}.
|
| Tissue Specificity |
Widely expressed. Expressed in adult and fetal heart, brain, lung, liver, skeletal muscle and kidney. Expressed in adult pancreas and placenta and in fetal spleen abd thymus. {ECO:0000269|PubMed:12093374}.
|