| Gene Symbol |
SYCP3
|
| Entrez Gene |
50511
|
| Alt Symbol |
COR1, SCP3, SPGF4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
synaptonemal complex protein 3
|
| Other Description |
-
|
| Swissprots |
Q8IZU3
|
| Accessions |
EAW97678 EAW97679 EAW97680 EAW97681 Q8IZU3 AF492003 AAN06611 AF517774 AAP47204 AI015251 AK125930 BC062662 AAH62662 BG201028 BG202454 BQ428625 XM_005268922 XP_005268979 XM_005268924 XP_005268981 XM_005268925 XP_005268982 XM_005268926 XP_005268983 XM_005268927 XP_005268984 XM_011538421 XP_011536723 NM_001177948 NP_001171419 NM_001177949 NP_001171420 NM_153694 NP_710161
|
| Function |
Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed. {ECO:0000250}.
|
| Tissue Specificity |
Testis-specific. {ECO:0000269|PubMed:12213195, ECO:0000269|PubMed:14643120}.
|
![Western Blot: SCP3 Overexpression Lysate (Adult Normal) [NBL1-16635] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SCP3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9287_SCP3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16635-img0002.jpg)