Gene Symbol | SYCP3 |
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Entrez Gene | 50511 |
Alt Symbol | COR1, SCP3, SPGF4 |
Species | Human |
Gene Type | protein-coding |
Description | synaptonemal complex protein 3 |
Other Description | - |
Swissprots | Q8IZU3 |
Accessions | EAW97678 EAW97679 EAW97680 EAW97681 Q8IZU3 AF492003 AAN06611 AF517774 AAP47204 AI015251 AK125930 BC062662 AAH62662 BG201028 BG202454 BQ428625 XM_005268922 XP_005268979 XM_005268924 XP_005268981 XM_005268925 XP_005268982 XM_005268926 XP_005268983 XM_005268927 XP_005268984 XM_011538421 XP_011536723 NM_001177948 NP_001171419 NM_001177949 NP_001171420 NM_153694 NP_710161 |
Function | Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed. {ECO:0000250}. |
Tissue Specificity | Testis-specific. {ECO:0000269|PubMed:12213195, ECO:0000269|PubMed:14643120}. |
SCP-3 CRISPR/Cas9 KO Plasmid (h) - sc-418308 from Santa Cruz Biotechnology
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SCP-3 HDR Plasmid (h) - sc-418308-HDR from Santa Cruz Biotechnology
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SCP-3 Double Nickase Plasmid (h) - sc-418308-NIC from Santa Cruz Biotechnology
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SCP-3 Double Nickase Plasmid (h2) - sc-418308-NIC-2 from Santa Cruz Biotechnology
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SCP-3 CRISPR Activation Plasmid (h) - sc-418308-ACT from Santa Cruz Biotechnology
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SCP-3 CRISPR Activation Plasmid (h2) - sc-418308-ACT-2 from Santa Cruz Biotechnology
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SCP-3 Lentiviral Activation Particles (h) - sc-418308-LAC from Santa Cruz Biotechnology
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SCP-3 Lentiviral Activation Particles (h2) - sc-418308-LAC-2 from Santa Cruz Biotechnology
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SCP-3 siRNA (h) - sc-44882 from Santa Cruz Biotechnology
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SCP-3 shRNA Plasmid (h) - sc-44882-SH from Santa Cruz Biotechnology
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SCP-3 shRNA (h) Lentiviral Particles - sc-44882-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU093361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20880 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20880 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02069 from Sigma-Aldrich
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SYCP3 siRNA (Human) - CRH9380 from Cohesion Biosciences
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SYCP3 - MBS8233925 from MyBioSource
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shRNA set against Human SYCP3 (NM_153694.4) - SHH421532 from Creative biogene
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Human SYCP3 siRNA - orb269882 from Biorbyt
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SYCP3 shRNA Plasmid (Human) - CHH9380 from Cohesion Biosciences
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SYCP3 miRNA 3'UTR clone - MiUTR4H-TG12557 from Creative biogene
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