Ube2l3

Gene Symbol Ube2l3
Entrez Gene 22195
Alt Symbol C79827, UbcM4, Ubce7
Species Mouse
Gene Type protein-coding
Description ubiquitin-conjugating enzyme E2L 3
Other Description ubiquitin carrier protein L3|ubiquitin-conjugating enzyme 7|ubiquitin-conjugating enzyme E2 L3|ubiquitin-protein ligase L3
Swissprots P68037
Accessions AAB36018 AAD10128 EDK97452 P68037 AJ130961 CAA10265 AK007265 BAB24925 AK152522 BAE31282 AK159876 BAE35448 AK165620 BAE38300 AK167847 BAE39867 AK187045 AK189509 AK208192 BC049075 BC057959 BC093503 AAH93503 BC106149 AAI06150 X97042 CAA65755 XM_006522004 XP_006522067 NM_009456 NP_033482
Function Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PARK2 and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down- regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Top Pathways Ubiquitin mediated proteolysis

UBE2L3 CRISPR/Cas9 KO Plasmid (m) - sc-423578 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

UBE2L3 HDR Plasmid (m) - sc-423578-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

UBE2L3 Double Nickase Plasmid (m) - sc-423578-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

UBE2L3 Double Nickase Plasmid (m2) - sc-423578-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

UBE2L3 CRISPR Activation Plasmid (m) - sc-423578-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

UBE2L3 CRISPR Activation Plasmid (m2) - sc-423578-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

UBE2L3 Lentiviral Activation Particles (m) - sc-423578-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

UBE2L3 Lentiviral Activation Particles (m2) - sc-423578-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

UBE2L3 siRNA (m) - sc-61747 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

UBE2L3 shRNA Plasmid (m) - sc-61747-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

UBE2L3 shRNA (m) Lentiviral Particles - sc-61747-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU197671 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN43815 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND43815 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

UBE2L3 siRNA (Mouse) - CRM4310 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

UBE2L3 - MBS8236325 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse Ube2l3(NM_009456.2) - SHL111288 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse UBE2L3 siRNA - orb283786 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

UBE2L3 shRNA Plasmid (Mouse) - CHM4310 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

UBE2L3 miRNA 3'UTR clone - MiUTR1M-12391 from Creative biogene

Species Reactivities Mouse
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