| Gene Symbol |
NDUFA4
|
| Entrez Gene |
4697
|
| Alt Symbol |
CI-9k, CI-MLRQ, MLRQ
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NDUFA4, mitochondrial complex associated
|
| Other Description |
Complex I 9kDa subunit|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa|NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4|NADH-ubiquinone oxidoreductase MLRQ subunit|complex I-MLRQ|cytochrome c oxidase subunit NDUFA4
|
| Swissprots |
O00483 Q6FHN5 A4D109
|
| Accessions |
EAL24297 EAW93630 EAW93631 EAW93632 O00483 AF201077 AAF09253 AK024837 AK130950 BC101794 AAI01795 BC101796 AAI01797 BC105295 AAI05296 BG623521 CR407618 CAG28546 CR541716 CAG46517 U94586 AAB52726 NM_002489 NP_002480
|
| Function |
Cytochrome c oxidase (COX, complex IV) is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. Required for complex IV maintenance. {ECO:0000269|PubMed:22902835}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:23746447}; Peripheral membrane protein {ECO:0000269|PubMed:23746447}; Matrix side {ECO:0000269|PubMed:23746447}.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|