| Gene Symbol | ARSB |
|---|---|
| Entrez Gene | 411 |
| Alt Symbol | ASB, G4S, MPS6 |
| Species | Human |
| Gene Type | protein-coding |
| Description | arylsulfatase B |
| Other Description | N-acetylgalactosamine-4-sulfatase |
| Swissprots | P15848 Q9UDI9 B2RC20 Q8N322 |
| Accessions | AAB19988 CAA51272 EAW95821 EAW95822 EAW95823 P15848 AI244301 AI457798 AI821478 AK026942 AK290865 BAF83554 AK314903 BAG37417 AL135624 AW236748 BC029051 AAH29051 BC036609 BM664932 BQ216635 BQ775217 BX350102 BX364854 BX369127 J05225 AAA51784 M32373 AAA51779 XM_005248506 XP_005248563 XM_006714615 XP_006714678 XM_011543390 XP_011541692 XM_011543391 XP_011541693 XM_011543392 XP_011541694 XM_011543393 XP_011541695 NM_000046 NP_000037 NM_198709 NP_942002 |
| Function | Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (PubMed:19306108). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (PubMed:19306108). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). {ECO:0000250|UniProtKB:P50430, ECO:0000269|PubMed:19306108}. |
| Subcellular Location | Lysosome. Cell surface {ECO:0000250|UniProtKB:P50429}. |
| Top Pathways | Lysosome, Glycosaminoglycan degradation |