Gene Symbol | ARSB |
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Entrez Gene | 411 |
Alt Symbol | ASB, G4S, MPS6 |
Species | Human |
Gene Type | protein-coding |
Description | arylsulfatase B |
Other Description | N-acetylgalactosamine-4-sulfatase |
Swissprots | P15848 Q9UDI9 B2RC20 Q8N322 |
Accessions | AAB19988 CAA51272 EAW95821 EAW95822 EAW95823 P15848 AI244301 AI457798 AI821478 AK026942 AK290865 BAF83554 AK314903 BAG37417 AL135624 AW236748 BC029051 AAH29051 BC036609 BM664932 BQ216635 BQ775217 BX350102 BX364854 BX369127 J05225 AAA51784 M32373 AAA51779 XM_005248506 XP_005248563 XM_006714615 XP_006714678 XM_011543390 XP_011541692 XM_011543391 XP_011541693 XM_011543392 XP_011541694 XM_011543393 XP_011541695 NM_000046 NP_000037 NM_198709 NP_942002 |
Function | Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (PubMed:19306108). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (PubMed:19306108). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). {ECO:0000250|UniProtKB:P50430, ECO:0000269|PubMed:19306108}. |
Subcellular Location | Lysosome. Cell surface {ECO:0000250|UniProtKB:P50429}. |
Top Pathways | Lysosome, Glycosaminoglycan degradation |
Arylsulfatase B CRISPR/Cas9 KO Plasmid (h) - sc-406463 from Santa Cruz Biotechnology
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Arylsulfatase B HDR Plasmid (h) - sc-406463-HDR from Santa Cruz Biotechnology
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Arylsulfatase B Double Nickase Plasmid (h) - sc-406463-NIC from Santa Cruz Biotechnology
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Arylsulfatase B Double Nickase Plasmid (h2) - sc-406463-NIC-2 from Santa Cruz Biotechnology
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Arylsulfatase B CRISPR Activation Plasmid (h) - sc-406463-ACT from Santa Cruz Biotechnology
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Arylsulfatase B CRISPR Activation Plasmid (h2) - sc-406463-ACT-2 from Santa Cruz Biotechnology
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Arylsulfatase B Lentiviral Activation Particles (h) - sc-406463-LAC from Santa Cruz Biotechnology
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Arylsulfatase B Lentiviral Activation Particles (h2) - sc-406463-LAC-2 from Santa Cruz Biotechnology
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Arylsulfatase B siRNA (h) - sc-91951 from Santa Cruz Biotechnology
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Arylsulfatase B shRNA Plasmid (h) - sc-91951-SH from Santa Cruz Biotechnology
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Arylsulfatase B shRNA (h) Lentiviral Particles - sc-91951-V from Santa Cruz Biotechnology
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Arylsulfatase B/ARSB RNAi - H00000411-R02 from Novus Biologicals
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Arylsulfatase B/ARSB RNAi - H00000411-R01 from Novus Biologicals
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MISSION® esiRNA - EHU140041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1608 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1608 from Sigma-Aldrich
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ARSB siRNA (Human) - CRH0299 from Cohesion Biosciences
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ARSB - MBS8205929 from MyBioSource
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shRNA set against Human ARSB(NM_000046.3) - SHG074773 from Creative biogene
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shRNA set against Human ARSB(NM_198709.2) - SHG074809 from Creative biogene
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Human ARSB siRNA - orb260801 from Biorbyt
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ARSB shRNA Plasmid (Human) - CHH0299 from Cohesion Biosciences
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ARSB miRNA 3'UTR clone - MiUTR1H-00604 from Creative biogene
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ARSB miRNA 3'UTR clone - MiUTR1H-00605 from Creative biogene
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