Gene Symbol | ARSB |
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Entrez Gene | 411 |
Alt Symbol | ASB, G4S, MPS6 |
Species | Human |
Gene Type | protein-coding |
Description | arylsulfatase B |
Other Description | N-acetylgalactosamine-4-sulfatase |
Swissprots | P15848 Q9UDI9 B2RC20 Q8N322 |
Accessions | AAB19988 CAA51272 EAW95821 EAW95822 EAW95823 P15848 AI244301 AI457798 AI821478 AK026942 AK290865 BAF83554 AK314903 BAG37417 AL135624 AW236748 BC029051 AAH29051 BC036609 BM664932 BQ216635 BQ775217 BX350102 BX364854 BX369127 J05225 AAA51784 M32373 AAA51779 XM_005248506 XP_005248563 XM_006714615 XP_006714678 XM_011543390 XP_011541692 XM_011543391 XP_011541693 XM_011543392 XP_011541694 XM_011543393 XP_011541695 NM_000046 NP_000037 NM_198709 NP_942002 |
Function | Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (PubMed:19306108). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (PubMed:19306108). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). {ECO:0000250|UniProtKB:P50430, ECO:0000269|PubMed:19306108}. |
Subcellular Location | Lysosome. Cell surface {ECO:0000250|UniProtKB:P50429}. |
Top Pathways | Lysosome, Glycosaminoglycan degradation |
Human ARSB protein fragment - ab117054 from Abcam
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ARSB / Arylsulfatase B Antibody Blocking Peptide - LS-E21537 from LifeSpan Bioscience
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ARSB / Arylsulfatase B Antibody Blocking Peptide - LS-E8982 from LifeSpan Bioscience
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ARSB / Arylsulfatase B Antibody Blocking Peptide - LS-E8983 from LifeSpan Bioscience
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ARSB / Arylsulfatase B Antibody Blocking Peptide - LS-E26477 from LifeSpan Bioscience
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Recombinant Human Arylsulfatase B/ARSB Protein - H00000411-Q01 from Novus Biologicals
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ARSB-Antibody-Center-Blocking-Peptide - BP7460c from Abgent, a WuXi AppTec company
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ARSB-Antibody-C-term-Blocking-Peptide - BP7460b from Abgent, a WuXi AppTec company
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ARSB blocking peptide - GTX88904-PEP from GeneTex
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Recombinant Human Arylsulfatase B/ARSB, CF - 4415-SU-010 from R&D Systems
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Human ARSB protein - orb244030 from Biorbyt
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Human ARSB protein - orb245754 from Biorbyt
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Arsb Blocking Peptide - 33R-9015 from Fitzgerald
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Arylsulfatase B Blocking Peptide - abx161281 from Abbexa
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ARSB Peptide - AC21-1314-P from Abcore
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Arylsulfatase B - H00000411-Q01-10 from Acris Antibodies
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Arylsulfatase B - H00000411-Q01-25 from Acris Antibodies
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ARSB Peptide - 7465P from ProSci
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Arylsulfatase B Peptide - 45-296P from ProSci
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ARSB fusion protein - ag6924 from Proteintech Group
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ARSB fusion protein - ag4083 from Proteintech Group
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Recombinant Human ARSB - ARSB-26104TH from Creative Biomart
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Recombinant Human ARSB, His-tagged - ARSB-1062H from Creative Biomart
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Recombinant Human ARSB, His-tagged - ARSB-1063H from Creative Biomart
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Recombinant Human enzyme N-acetylgalactosamine 4-sulfatase therapeutic protein (Galsulfase, Arylsulfatase B) - ARSB-P038H from Creative Biomart
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