Gene Symbol |
NUDT5
|
Entrez Gene |
11164
|
Alt Symbol |
YSA1, YSA1H, YSAH1, hYSAH1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
nudix (nucleoside diphosphate linked moiety X)-type motif 5
|
Other Description |
8-oxo-dGDP phosphatase|ADP-sugar pyrophosphatase
|
Swissprots |
Q9UH49 A8K516 Q6IAG0 Q9UKK9
|
Accessions |
EAW86320 EAW86321 EAW86322 Q9UKK9 AF155832 AAF06734 AF161464 AAF29079 AF218818 AAF25479 AK123731 AK291131 BAF83820 AK314144 BC000025 AAH00025 BU602000 CR457195 CAG33476 XM_011519304 XP_011517606 XM_011519305 XP_011517607 NM_014142 NP_054861
|
Function |
Hydrolyzes with similar activities ADP-ribose ADP- mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. {ECO:0000269|PubMed:17052728}.
|
Tissue Specificity |
Widely expressed. Most abundant in liver.
|
Top Pathways |
Purine metabolism
|