Gene Symbol | NUDT5 |
---|---|
Entrez Gene | 11164 |
Alt Symbol | YSA1, YSA1H, YSAH1, hYSAH1 |
Species | Human |
Gene Type | protein-coding |
Description | nudix (nucleoside diphosphate linked moiety X)-type motif 5 |
Other Description | 8-oxo-dGDP phosphatase|ADP-sugar pyrophosphatase |
Swissprots | Q9UH49 A8K516 Q6IAG0 Q9UKK9 |
Accessions | EAW86320 EAW86321 EAW86322 Q9UKK9 AF155832 AAF06734 AF161464 AAF29079 AF218818 AAF25479 AK123731 AK291131 BAF83820 AK314144 BC000025 AAH00025 BU602000 CR457195 CAG33476 XM_011519304 XP_011517606 XM_011519305 XP_011517607 NM_014142 NP_054861 |
Function | Hydrolyzes with similar activities ADP-ribose ADP- mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. {ECO:0000269|PubMed:17052728}. |
Tissue Specificity | Widely expressed. Most abundant in liver. |
Top Pathways | Purine metabolism |