Gene Symbol |
GMPR
|
Entrez Gene |
2766
|
Alt Symbol |
GMPR1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
guanosine monophosphate reductase
|
Other Description |
GMP reductase 1|guanine monophosphate reductase|guanosine 5'-monophosphate oxidoreductase 1|guanosine monophosphate reductase 1
|
Swissprots |
Q96HQ6 P36959
|
Accessions |
AAA52503 AAA53106 EAW55368 EAW55369 P36959 BC008281 AAH08281 EU831974 ACE87415 EU832067 ACE86729 HQ447824 ADQ32308 M24470 AAA52498 XM_011514508 XP_011512810 NM_006877 NP_006868
|
Function |
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
|
Top Pathways |
Purine metabolism
|