Gene Symbol | GMPR |
---|---|
Entrez Gene | 2766 |
Alt Symbol | GMPR1 |
Species | Human |
Gene Type | protein-coding |
Description | guanosine monophosphate reductase |
Other Description | GMP reductase 1|guanine monophosphate reductase|guanosine 5'-monophosphate oxidoreductase 1|guanosine monophosphate reductase 1 |
Swissprots | Q96HQ6 P36959 |
Accessions | AAA52503 AAA53106 EAW55368 EAW55369 P36959 BC008281 AAH08281 EU831974 ACE87415 EU832067 ACE86729 HQ447824 ADQ32308 M24470 AAA52498 XM_011514508 XP_011512810 NM_006877 NP_006868 |
Function | Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. |
Top Pathways | Purine metabolism |