EIF4B

Gene Symbol	EIF4B
Entrez Gene	1975
Alt Symbol	EIF-4B, PRO1843
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 4B
Other Description	-
Swissprots	Q6GPH5 P23588 Q8WYK5 Q4G0E3 Q6IB46 Q53HQ2 B4DS13
Accessions	CAA39265 EAW96657 P23588 AB076839 BAB82380 AF119854 AAF69608 AK092188 AK222528 BAD96248 AK293731 BAG57157 AK299329 BAG61335 AK299510 BAG61463 AK299526 BAG61475 AK307496 AK310244 AK312187 BAG35120 BC001097 AAH01097 BC007745 BC013994 BC047302 BC061907 BC064029 BC073139 AAH73139 BC073154 AAH73154 BC098437 AAH98437 BG547613 BP236621 BP243230 BU431305 BU902688 CR456958 CAG33239 CR627377 CAH10474 DC403237 XM_006719274 XP_006719337 NM_018507 NM_001300821 NP_001287750 NM_001417 NP_001408
Function	Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Top Pathways	RNA transport, PI3K-Akt signaling pathway, Proteoglycans in cancer, mTOR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence® eIF4B siRNA - 6416 from Cell Signaling Technology Category siRNA

eIF4B CRISPR/Cas9 KO Plasmid (h) - sc-402494 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

eIF4B HDR Plasmid (h) - sc-402494-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

eIF4B Double Nickase Plasmid (h) - sc-402494-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

eIF4B Double Nickase Plasmid (h2) - sc-402494-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

eIF4B CRISPR Activation Plasmid (h) - sc-402494-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

eIF4B CRISPR Activation Plasmid (h2) - sc-402494-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

eIF4B Lentiviral Activation Particles (h) - sc-402494-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

eIF4B Lentiviral Activation Particles (h2) - sc-402494-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

eIF4B siRNA (h) - sc-77253 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

eIF4B shRNA Plasmid (h) - sc-77253-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

eIF4B shRNA (h) Lentiviral Particles - sc-77253-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

eIF4B RNAi - H00001975-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU110071 from Sigma-Aldrich Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN7774 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7774 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10930 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10930

EIF4B siRNA (Human) - CRH1366 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

EIF4B - MBS8200490 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human EIF4B(NM_001417.4) - SHH029639 from Creative biogene Category siRNA Species Reactivities Human

EIF4B shRNA Plasmid (Human) - CHH1366 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

EIF4B miRNA 3'UTR clone - MiUTR1H-03172 from Creative biogene Species Reactivities Human

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