| Gene Symbol |
HIST2H2AA3
|
| Entrez Gene |
8337
|
| Alt Symbol |
H2A, H2A.2, H2A/O, H2A/q, H2AFO, H2a-615, HIST2H2AA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 2, H2aa3
|
| Other Description |
H2A histone family, member O|histone 2, H2aa3|histone H2A type 2-A
|
| Swissprots |
Q6FI13 P20670 B2R5F0
|
| Accessions |
AAA35945 AAN59957 CAI12562 EAW50859 Q6FI13 AK312163 BAG35097 BC001629 BC019308 BC096705 AAH96705 BC096739 AAH96739 BC098171 AAH98171 BC152787 AAI52788 CR536525 CAG38762 CR541872 CAG46670 L19779 AAC24465 NM_003516 NP_003507
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Top Pathways |
Systemic lupus erythematosus, Alcoholism
|