Gene Symbol |
MTUS2
|
Entrez Gene |
23281
|
Alt Symbol |
CAZIP, ICIS, KIAA0774, TIP150
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
microtubule associated tumor suppressor candidate 2
|
Other Description |
+TIP of 150 kDa|cardiac zipper protein|microtubule plus-end tracking protein TIP150|microtubule-associated tumor suppressor candidate 2|tracking protein of 150 kDa
|
Swissprots |
Q8N5E2 Q08E97 Q5JR59 O94872 B4DF81 Q5JQR3 A7E292
|
Accessions |
EAX08439 EAX08440 Q5JR59 AB018317 BAA34494 AK293970 BAG57342 AK301633 BAG63116 AK302516 BAG63792 BC032481 AAH32481 BC119654 AAI19655 BC119655 AAI19656 BC129985 AAI29986 BC150245 AAI50246 BM906724 BU788127 HQ447180 ADQ31667 XM_011535019 XP_011533321 XM_011535020 XP_011533322 XM_011535021 XP_011533323 XM_011535022 XP_011533324 XM_011535023 XP_011533325 NM_001033602 NP_001028774 NM_015233 NP_056048
|
Function |
Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip. {ECO:0000269|PubMed:19543227}.
|
Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19543227}. Note=Associated with the microtubule network at the growing distal tip (the plus-end) of microtubules.
|
Tissue Specificity |
Detected in embryonic stem cells differentiating to cardiomyocytes. {ECO:0000269|PubMed:19806667}.
|