Gene Symbol | MTUS2 |
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Entrez Gene | 23281 |
Alt Symbol | CAZIP, ICIS, KIAA0774, TIP150 |
Species | Human |
Gene Type | protein-coding |
Description | microtubule associated tumor suppressor candidate 2 |
Other Description | +TIP of 150 kDa|cardiac zipper protein|microtubule plus-end tracking protein TIP150|microtubule-associated tumor suppressor candidate 2|tracking protein of 150 kDa |
Swissprots | Q8N5E2 Q08E97 Q5JR59 O94872 B4DF81 Q5JQR3 A7E292 |
Accessions | EAX08439 EAX08440 Q5JR59 AB018317 BAA34494 AK293970 BAG57342 AK301633 BAG63116 AK302516 BAG63792 BC032481 AAH32481 BC119654 AAI19655 BC119655 AAI19656 BC129985 AAI29986 BC150245 AAI50246 BM906724 BU788127 HQ447180 ADQ31667 XM_011535019 XP_011533321 XM_011535020 XP_011533322 XM_011535021 XP_011533323 XM_011535022 XP_011533324 XM_011535023 XP_011533325 NM_001033602 NP_001028774 NM_015233 NP_056048 |
Function | Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip. {ECO:0000269|PubMed:19543227}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19543227}. Note=Associated with the microtubule network at the growing distal tip (the plus-end) of microtubules. |
Tissue Specificity | Detected in embryonic stem cells differentiating to cardiomyocytes. {ECO:0000269|PubMed:19806667}. |
MTUS2 CRISPR/Cas9 KO Plasmid (h) - sc-408841 from Santa Cruz Biotechnology
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MTUS2 HDR Plasmid (h) - sc-408841-HDR from Santa Cruz Biotechnology
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MTUS2 Double Nickase Plasmid (h) - sc-408841-NIC from Santa Cruz Biotechnology
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MTUS2 Double Nickase Plasmid (h2) - sc-408841-NIC-2 from Santa Cruz Biotechnology
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MTUS2 CRISPR Activation Plasmid (h) - sc-408841-ACT from Santa Cruz Biotechnology
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MTUS2 CRISPR Activation Plasmid (h2) - sc-408841-ACT-2 from Santa Cruz Biotechnology
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MTUS2 Lentiviral Activation Particles (h) - sc-408841-LAC from Santa Cruz Biotechnology
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MTUS2 Lentiviral Activation Particles (h2) - sc-408841-LAC-2 from Santa Cruz Biotechnology
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MTUS2 siRNA (h) - sc-75382 from Santa Cruz Biotechnology
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MTUS2 shRNA Plasmid (h) - sc-75382-SH from Santa Cruz Biotechnology
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MTUS2 shRNA (h) Lentiviral Particles - sc-75382-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU021421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14745 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14745 from Sigma-Aldrich
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MTUS2 siRNA (Human) - CRH8148 from Cohesion Biosciences
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shRNA set against Human MTUS2 (NM_001033602.2) - SHH346776 from Creative biogene
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shRNA set against Human KIAA0774(NM_015233.5) - SHL195048 from Creative biogene
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shRNA set against Human KIAA0774(NM_001033602.2) - SHL195066 from Creative biogene
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MTUS2 shRNA Plasmid (Human) - CHH8148 from Cohesion Biosciences
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MTUS2 miRNA 3'UTR clone - MiUTR1H-05228 from Creative biogene
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MTUS2 miRNA 3'UTR clone - MiUTR1H-05229 from Creative biogene
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