| Gene Symbol |
CLDN2
|
| Entrez Gene |
9075
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
claudin 2
|
| Other Description |
SP82|claudin-2
|
| Swissprots |
B2R6B9 P57739
|
| Accessions |
CAI72078 CAT04641 EAX02730 EAX02731 EAX02732 P57739 AA973123 AF177340 AAG17984 AF250558 AAF98151 AK075371 BAC11575 AK075405 BAG52130 AK312515 BAG35416 AY358474 AAQ88838 BC014424 AAH14424 BC071747 AAH71747 DA743944 DQ892216 ABM83142 DQ895412 ABM86338 NM_001171092 NP_001164563 NM_001171095 NP_001164566 NM_020384 NP_065117
|
| Function |
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}.
|
| Subcellular Location |
Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Top Pathways |
Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C
|
![Western Blot: Claudin 2 Overexpression Lysate (Adult Normal) [NBL1-09243] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Claudin 2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/14317_Claudin%25202%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-09243-img0002.jpg)