Gene Symbol | CLDN2 |
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Entrez Gene | 9075 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | claudin 2 |
Other Description | SP82|claudin-2 |
Swissprots | B2R6B9 P57739 |
Accessions | CAI72078 CAT04641 EAX02730 EAX02731 EAX02732 P57739 AA973123 AF177340 AAG17984 AF250558 AAF98151 AK075371 BAC11575 AK075405 BAG52130 AK312515 BAG35416 AY358474 AAQ88838 BC014424 AAH14424 BC071747 AAH71747 DA743944 DQ892216 ABM83142 DQ895412 ABM86338 NM_001171092 NP_001164563 NM_001171095 NP_001164566 NM_020384 NP_065117 |
Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}. |
Subcellular Location | Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C |
claudin-2 CRISPR/Cas9 KO Plasmid (h) - sc-402316 from Santa Cruz Biotechnology
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claudin-2 HDR Plasmid (h) - sc-402316-HDR from Santa Cruz Biotechnology
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claudin-2 Double Nickase Plasmid (h) - sc-402316-NIC from Santa Cruz Biotechnology
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claudin-2 Double Nickase Plasmid (h2) - sc-402316-NIC-2 from Santa Cruz Biotechnology
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claudin-2 CRISPR Activation Plasmid (h) - sc-402316-ACT from Santa Cruz Biotechnology
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claudin-2 CRISPR Activation Plasmid (h2) - sc-402316-ACT-2 from Santa Cruz Biotechnology
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claudin-2 Lentiviral Activation Particles (h) - sc-402316-LAC from Santa Cruz Biotechnology
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claudin-2 Lentiviral Activation Particles (h2) - sc-402316-LAC-2 from Santa Cruz Biotechnology
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claudin-2 siRNA (h) - sc-62124 from Santa Cruz Biotechnology
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claudin-2 shRNA Plasmid (h) - sc-62124-SH from Santa Cruz Biotechnology
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claudin-2 shRNA (h) Lentiviral Particles - sc-62124-V from Santa Cruz Biotechnology
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Claudin-2 RNAi - H00009075-R01 from Novus Biologicals
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MISSION® esiRNA - EHU067041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6181 from Sigma-Aldrich
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CLDN2 siRNA (Human) - CRH5991 from Cohesion Biosciences
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CLDN2 - MBS8227372 from MyBioSource
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shRNA set against Human CLDN2 (NM_020384.3) - SHH264741 from Creative biogene
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CLDN2 shRNA Plasmid (Human) - CHH5991 from Cohesion Biosciences
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