CPZ

Gene Symbol	CPZ
Entrez Gene	8532
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	carboxypeptidase Z
Other Description	metallocarboxypeptidase Z
Swissprots	Q96MX2 O00520 Q66K79
Accessions	EAW82332 EAW82333 EAW82334 EAW82335 Q66K79 AI270606 AK056317 BAB71147 AK127844 BAG54585 AW139378 BC006393 BC018913 BC080539 AAH80539 BF993977 BX338482 CV026874 DA050438 DA698835 DA704214 U83411 AAB58911 NM_001014447 NP_001014447 NM_001014448 NP_001014448 NM_003652 NP_003643
Function	Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing. {ECO:0000269|PubMed:11766880, ECO:0000269|PubMed:12417617, ECO:0000269|PubMed:9099699}.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:10671522}.
Tissue Specificity	In placenta, it is present within invasive trophoblasts and in the surrounding extracellular space. Also present in amnion cells, but is not readily apparent in the extracellular matrix of this cell type. Present in normal pituitary gland and neoplastic pituitary gland (especially POMC-, GH- and PRL-producing adenomas) (at protein level). Widely expressed. {ECO:0000269|PubMed:10671522, ECO:0000269|PubMed:12417617, ECO:0000269|PubMed:9099699}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CPZ CRISPR/Cas9 KO Plasmid (h) - sc-408788 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CPZ HDR Plasmid (h) - sc-408788-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CPZ Double Nickase Plasmid (h) - sc-408788-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CPZ Double Nickase Plasmid (h2) - sc-408788-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CPZ CRISPR Activation Plasmid (h) - sc-408788-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CPZ CRISPR Activation Plasmid (h2) - sc-408788-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CPZ Lentiviral Activation Particles (h) - sc-408788-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CPZ Lentiviral Activation Particles (h2) - sc-408788-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CPZ siRNA (h) - sc-89218 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CPZ shRNA Plasmid (h) - sc-89218-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CPZ shRNA (h) Lentiviral Particles - sc-89218-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CPZ RNAi - H00008532-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU141191 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6537 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6537 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CPZ siRNA (Human) - CRH5603 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CPZ RNAi - H00008532-R05 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CPZ RNAi - H00008532-R06 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CPZ - MBS8211412 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CP (NM_003652.3) - SHH268465 from Creative biogene Category siRNA Species Reactivities Human

CPZ shRNA Plasmid (Human) - CHH5603 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CPZ miRNA 3'UTR clone - MiUTR3H-05671 from Creative biogene Species Reactivities Human

CPZ miRNA 3'UTR clone - MiUTR3H-05672 from Creative biogene Species Reactivities Human

CPZ miRNA 3'UTR clone - MiUTR3H-05673 from Creative biogene Species Reactivities Human

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