Gene Symbol | CXCL14 |
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Entrez Gene | 9547 |
Alt Symbol | BMAC, BRAK, KEC, KS1, MIP-2g, MIP2G, NJAC, SCYB14 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-X-C motif) ligand 14 |
Other Description | C-X-C motif chemokine 14|CXC chemokine in breast and kidney|MIP-2 gamma|bolekine|breast and kidney|chemokine BRAK|small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK)|small-inducible cytokine B14|tumor-suppressing chemokine |
Swissprots | Q86U69 Q9NS21 Q9BTR1 Q6UW97 B3KQU8 O95715 |
Accessions | CAI72212 O95715 AB543622 BAI78370 AF073957 AAD03839 AF086340 AF106911 AAF78449 AF144103 AAD38944 AI743431 AK056613 AK075514 BAG52160 AM392840 CAL37718 AW614568 AY358906 AAQ89265 BC003513 AAH03513 BM670989 BT007080 AAP35743 BU729234 BX106404 NM_004887 NP_004878 |
Function | Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. {ECO:0000269|PubMed:10049774, ECO:0000269|PubMed:10946286}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte- derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes. {ECO:0000269|PubMed:10049774, ECO:0000269|PubMed:10854217, ECO:0000269|PubMed:10946286}. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
BRAK (C-14) - sc-27346 from Santa Cruz Biotechnology
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BRAK (H-86) - sc-366350 from Santa Cruz Biotechnology
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BRAK (P-21) - sc-130979 from Santa Cruz Biotechnology
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Anti-CXCL14 antibody - ab46010 from Abcam
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Anti-CXCL14 antibody (Biotin) - ab46008 from Abcam
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Anti-CXCL14 antibody [MM0213-12B24] - ab89323 from Abcam
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Anti-BRAK / CXCL14 Antibody (Biotin) - LS-C104495 from LifeSpan Bioscience
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Anti-BRAK / CXCL14 Antibody (aa73-86) - LS-C108907 from LifeSpan Bioscience
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Anti-BRAK / CXCL14 Antibody - LS-C285689 from LifeSpan Bioscience
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Anti-BRAK / CXCL14 Antibody (FITC) - LS-C316994 from LifeSpan Bioscience
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Anti-BRAK / CXCL14 Antibody (HRP) - LS-C316995 from LifeSpan Bioscience
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Anti-BRAK / CXCL14 Antibody (Biotin) - LS-C318788 from LifeSpan Bioscience
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Anti-BRAK / CXCL14 Antibody (C-Terminus) - LS-C30558 from LifeSpan Bioscience
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Anti-BRAK / CXCL14 Antibody (aa23-99) - LS-C293057 from LifeSpan Bioscience
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Anti-BRAK / CXCL14 Antibody (aa35-111) - LS-C314806 from LifeSpan Bioscience
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Anti-BRAK / CXCL14 Antibody (C-Terminus) IHC-plus⢠- LS-B6967 from LifeSpan Bioscience
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Anti-BRAK / CXCL14 Antibody - LS-C104496 from LifeSpan Bioscience
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CXCL14/BRAK Antibody - NBP1-31398 from Novus Biologicals
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CXCL14/BRAK Antibody - AF866 from Novus Biologicals
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CXCL14/BRAK Antibody - NBP1-46118 from Novus Biologicals
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CXCL14/BRAK Antibody (MM0213-12B24) - NBP2-12224 from Novus Biologicals
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CXCL14/BRAK Antibody [Biotin] - BAF866 from Novus Biologicals
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CXCL14/BRAK Antibody (131107) [Biotin] - BAM8661 from Novus Biologicals
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Anti-CXCL14 antibody produced in rabbit - SAB2107840 from Sigma-Aldrich
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Anti-CXCL14 antibody produced in rabbit - SAB2700387 from Sigma-Aldrich
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