Gene Symbol | CXCL14 |
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Entrez Gene | 9547 |
Alt Symbol | BMAC, BRAK, KEC, KS1, MIP-2g, MIP2G, NJAC, SCYB14 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-X-C motif) ligand 14 |
Other Description | C-X-C motif chemokine 14|CXC chemokine in breast and kidney|MIP-2 gamma|bolekine|breast and kidney|chemokine BRAK|small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK)|small-inducible cytokine B14|tumor-suppressing chemokine |
Swissprots | Q86U69 Q9NS21 Q9BTR1 Q6UW97 B3KQU8 O95715 |
Accessions | CAI72212 O95715 AB543622 BAI78370 AF073957 AAD03839 AF086340 AF106911 AAF78449 AF144103 AAD38944 AI743431 AK056613 AK075514 BAG52160 AM392840 CAL37718 AW614568 AY358906 AAQ89265 BC003513 AAH03513 BM670989 BT007080 AAP35743 BU729234 BX106404 NM_004887 NP_004878 |
Function | Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. {ECO:0000269|PubMed:10049774, ECO:0000269|PubMed:10946286}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte- derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes. {ECO:0000269|PubMed:10049774, ECO:0000269|PubMed:10854217, ECO:0000269|PubMed:10946286}. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
Active human CXCL14 full length protein - ab50043 from Abcam
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Active human CXCL14 full length protein - ab138785 from Abcam
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Human CXCL14 full length protein - ab174986 from Abcam
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Human CXCL14 peptide - ab36621 from Abcam
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BRAK / CXCL14 Antibody Blocking Peptide - LS-E10736 from LifeSpan Bioscience
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BRAK / CXCL14 Antibody Blocking Peptide - LS-E27188 from LifeSpan Bioscience
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CXCL14/BRAK Recombinant Protein - H00009547-P01 from Novus Biologicals
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CXCL14-Antibody-C-term-Blocking-Peptide - BP8815b from Abgent, a WuXi AppTec company
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CXCL14 Recombinant Protein (Active) - GTX48087-PRO from GeneTex
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CXCL14 blocking peptide - GTX88308-PEP from GeneTex
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Recombinant Human CXCL14/BRAK, CF - 866-CX-025 from R&D Systems
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BRAK Protein (OPPA01591) - OPPA01591 from Aviva Systems Biology
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Human CXCL14 protein (Native) - orb138663 from Biorbyt
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Brak protein - orb108490 from Biorbyt
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Mouse BRAK protein - orb168011 from Biorbyt
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Human BRAK protein - orb80651 from Biorbyt
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Human BRAK protein - orb168180 from Biorbyt
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Murine CXCL14 protein - orb223912 from Biorbyt
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CXCL14 peptide - orb72582 from Biorbyt
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BRAK protein - 30R-AB037 from Fitzgerald
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CXCL14 Blocking Peptide - 33R-10587 from Fitzgerald
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CXCL14 Blocking Peptide - 33R-3699 from Fitzgerald
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CXCL14 Peptide - AC21-2008-P from Abcore
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CXCL14 / BRAK - PA271 from Acris Antibodies
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CXCL14 / BRAK - PA271X from Acris Antibodies
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