| Gene Symbol |
PTGER2
|
| Entrez Gene |
5732
|
| Alt Symbol |
EP2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
prostaglandin E receptor 2 (subtype EP2), 53kDa
|
| Other Description |
PGE receptor EP2 subtype|PGE2 receptor EP2 subtype|prostaglandin E receptor 2 (subtype EP2), 53kD|prostaglandin E2 receptor EP2 subtype|prostanoid EP2 receptor
|
| Swissprots |
Q52LG8 D3DSC0 P43116
|
| Accessions |
AAD44177 ABD48958 EAW65652 EAW65653 EAW65654 P43116 AY275471 AAP32303 BC093927 AAH93927 BC093929 AAH93929 BE739744 BF029797 BM986745 BQ014559 CF132756 CN484094 CR977661 U19487 AAA61681 X83868 CAA58749 NM_000956 NP_000947
|
| Function |
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Placenta and lung.
|
| Top Pathways |
Inflammatory mediator regulation of TRP channels, cAMP signaling pathway, Neuroactive ligand-receptor interaction
|