Gene Symbol | PTGER2 |
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Entrez Gene | 5732 |
Alt Symbol | EP2 |
Species | Human |
Gene Type | protein-coding |
Description | prostaglandin E receptor 2 (subtype EP2), 53kDa |
Other Description | PGE receptor EP2 subtype|PGE2 receptor EP2 subtype|prostaglandin E receptor 2 (subtype EP2), 53kD|prostaglandin E2 receptor EP2 subtype|prostanoid EP2 receptor |
Swissprots | Q52LG8 D3DSC0 P43116 |
Accessions | AAD44177 ABD48958 EAW65652 EAW65653 EAW65654 P43116 AY275471 AAP32303 BC093927 AAH93927 BC093929 AAH93929 BE739744 BF029797 BM986745 BQ014559 CF132756 CN484094 CR977661 U19487 AAA61681 X83868 CAA58749 NM_000956 NP_000947 |
Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Placenta and lung. |
Top Pathways | Inflammatory mediator regulation of TRP channels, cAMP signaling pathway, Neuroactive ligand-receptor interaction |
EP2 CRISPR/Cas9 KO Plasmid (h) - sc-401464 from Santa Cruz Biotechnology
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EP2 HDR Plasmid (h) - sc-401464-HDR from Santa Cruz Biotechnology
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EP2 Double Nickase Plasmid (h) - sc-401464-NIC from Santa Cruz Biotechnology
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EP2 Double Nickase Plasmid (h2) - sc-401464-NIC-2 from Santa Cruz Biotechnology
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EP2 CRISPR Activation Plasmid (h) - sc-401464-ACT from Santa Cruz Biotechnology
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EP2 CRISPR Activation Plasmid (h2) - sc-401464-ACT-2 from Santa Cruz Biotechnology
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EP2 Lentiviral Activation Particles (h) - sc-401464-LAC from Santa Cruz Biotechnology
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EP2 Lentiviral Activation Particles (h2) - sc-401464-LAC-2 from Santa Cruz Biotechnology
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EP2 siRNA (h) - sc-40171 from Santa Cruz Biotechnology
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EP2 shRNA Plasmid (h) - sc-40171-SH from Santa Cruz Biotechnology
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EP2 shRNA (h) Lentiviral Particles - sc-40171-V from Santa Cruz Biotechnology
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PTGER2 RNAi - H00005732-R02 from Novus Biologicals
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MISSION® esiRNA - EHU119261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1849 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1849 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08593 from Sigma-Aldrich
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PTGER2 siRNA (Human) - CRH3876 from Cohesion Biosciences
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shRNA set against Human PTGER2 (NM_000956.3) - SHH385988 from Creative biogene
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Human PTGER2 siRNA - orb264378 from Biorbyt
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PTGER2 shRNA Plasmid (Human) - CHH3876 from Cohesion Biosciences
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PTGER2 miRNA 3'UTR clone - MiUTR3H-01851 from Creative biogene
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