| Gene Symbol | henmt1 |
|---|---|
| Entrez Gene | 550540 |
| Alt Symbol | hen1, si:ch211-199m3.6, zgc:110175 |
| Species | Zebrafish |
| Gene Type | protein-coding |
| Description | HEN1 methyltransferase homolog 1 (Arabidopsis) |
| Other Description | small RNA 2'-O-methyltransferase |
| Swissprots | Q5RH79 Q568P9 |
| Accessions | Q568P9 BC092772 AAH92772 BC165189 AAI65189 XM_009294718 XP_009292993 NM_001017842 NP_001017842 |
| Function | Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation and adenylation activities and subsequent degradation. Stabilization of piRNAs is essential for oocyte development. {ECO:0000269|PubMed:20859253}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20859253}. Note=Component of the meiotic nuage, also named P granule, a germ- cell-specific organelle required to repress transposon activity during meiosis. |
| Tissue Specificity | Gonad-specific. {ECO:0000269|PubMed:20859253}. |
Recombinant Zebrafish HENMT1 - HENMT1-2566Z from Creative Biomart
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Recombinant Danio rerio Small RNA 2'-O-methyltransferase(henmt1) - CSB-YP707091DIL CSB-EP707091DIL CSB-BP707091DIL CSB-MP707091DIL from Cusabio
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Small RNA 2'-O-methyltransferase (henmt1), Recombinant Protein - MBS1305586 from MyBioSource
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