IL4R

Gene Symbol	IL4R
Entrez Gene	3566
Alt Symbol	CD124, IL-4RA, IL4RA
Species	Human
Gene Type	protein-coding
Description	interleukin 4 receptor
Other Description	IL-4 receptor subunit alpha|IL4R nirs variant 1|interleukin-4 receptor alpha chain|interleukin-4 receptor subunit alpha
Swissprots	Q9H188 Q9H187 Q96P01 B9EKU8 H3BSY5 Q9H183 Q9H186 P24394 Q9H185 B4E076 Q9H184 Q9H181 Q9H182
Accessions	AAC23495 AAL12163 CAC20445 CAC20446 CAC20447 CAC20448 CAC20449 CAC20450 CAC20451 CAC20452 CAJ01243 EAW55750 P24394 AA838318 AB102798 BAD89389 AK223591 BAD97311 AK303255 BAG64338 AK314863 BAG37378 BC110343 BC136365 AAI36366 BC151131 AAI51132 BX479288 DA492909 EF173858 ABM53131 X52425 CAA36672 XM_005255308 XP_005255365 XM_006721043 XP_006721106 XM_011545825 XP_011544127 XM_011545826 XP_011544128 XM_011545827 XP_011544129 XM_011545828 XP_011544130 XM_011545829 XP_011544131 XM_011545830 XP_011544132 XM_011545831 XP_011544133 XM_011545832 XP_011544134 XM_011545833 XP_011544135 XM_011545834 XP_011544136 NM_000418 NP_000409 NM_001257406 NP_001244335 NM_001257407 NP_001244336 NM_001257997 NP_001244926 NM_001008699
Function	Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. {ECO:0000269|PubMed:8124718}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Isoform 1 and isoform 2 are highly expressed in activated T-cells.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Inflammatory bowel disease (IBD)

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IL-4 Receptor (CD124) Human ELISA Kit - ab46022 from Abcam Category ELISA Kit Prices $489.00, $734.00 Sizes 1 x 96 tests, 2 x 96 tests Sensitivity < 11.5 pg/ml Range 31.25 pg/ml - 1000 pg/ml

Human IL4R / CD124 ELISA Kit (Sandwich ELISA) - LS-F4458 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 15.63-1000 pg/ml

Mouse/Human IL4R / CD124 ELISA Kit (Cell-Based ELISA) - LS-F2079 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 15.63-1000 pg/ml

Mouse/Human Phospho-IL4R / CD124 (Tyr497) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1398 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 15.63-1000 pg/ml

Mouse/Human/Rat Phospho-IL4R / CD124 (Ser18) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1263 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 15.63-1000 pg/ml

Human IL4R / CD124 ELISA Kit (Sandwich ELISA) - LS-F11797 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 Range 15.63-1000 pg/ml

Human IL4R ELISA Kit - abx151947 from Abbexa Category ELISA Kit Sensitivity 5.8 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Interleukin 4 Receptor (IL4R), Human, ELISA Kit - SEC031Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 5.8pg/mL Range 15.6-1,000pg/mL

Interleukin 4 receptor (IL4R/CD124), Human, ELISA Kit - CSB-E13936h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Interleukin 4 Receptor, IL4R/CD124, Human, ELISA Kit - YHB1743Hu from ARP American Research Products Category ELISA Kit

Interleukin-4 receptor subunit alpha (IL4R), Human, ELISA Kit - E01I0434 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Interleukin-4 receptor subunit alpha, IL4R, Human, ELISA Kit - E2031h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 15.6-1000 pg/mL

Custom Human IL-4 R alpha ELISA - ELH-IL4Ra from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

IL-4R/CD124 Colorimetric Cell-Based ELISA Kit - CB5366 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Myosin regulatory light chain 2 (Phospho-Ser18) Colorimetric Cell-Based ELISA Kit - CBP1263 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

IL-4R/CD124 (Phospho-Tyr497) Colorimetric Cell-Based ELISA Kit - CBP1420 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

CD124, ELISA Kit - MBS335451 from MyBioSource Category ELISA Kit Prices $305.00, $470.00, $675.00 Sizes 1x48 wells (Pre-Coated), 1x96 wells (Pre-Coated), 2x96 wells (Pre-Coated) Sensitivity The sensitivity, minimum detectable dose of human IL-4R using this IL-4R ELISA kit was found to be 11.5 pg/ml. This was determined by adding 3 standard deviations to the mean OD obtained when the zero standard was assayed 32 times.

Interleukin 4 Receptor, ELISA Kit - MBS101155 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 4 Receptor, ELISA Kit - MBS072285 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 4 Receptor, ELISA Kit - MBS099431 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 4 Receptor, ELISA Kit - MBS047725 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 4 Receptor, ELISA Kit - MBS060525 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 4 Receptor, ELISA Kit - MBS057536 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

interleukin 4 receptor, ELISA Kit - MBS700113 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human IL4R/CD124 is typically less than 0.039 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.156 ng/ml -10 ng/ml.

Interleukin 4 Receptor, ELISA Kit - MBS081643 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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