Gene Symbol | CTSL |
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Entrez Gene | 1514 |
Alt Symbol | CATL, CTSL1, MEP |
Species | Human |
Gene Type | protein-coding |
Description | cathepsin L |
Other Description | cathepsin L1|major excreted protein |
Swissprots | Q96QJ0 P07711 Q6IAV1 |
Accessions | AAA66974 AAN87068 CAY55960 CAY55961 EAW62731 EAW62732 EAW62733 EAW62734 EAW62735 EAW62736 P07711 AF217997 AAG17239 AF304301 AAM89516 AF467444 AAQ05021 AK055599 AK075100 BAG52066 AL832167 AW270438 BC012612 AAH12612 BC142983 AAI42984 BI824449 BI829385 BM680778 BX537395 CAD97637 BX647101 BX647102 BX647413 BX647434 BX647435 BX648848 BX648849 BX649140 CB963086 CR457053 CAG33334 DN993009 DQ892930 ABM83856 DQ896179 ABM87178 X05256 CAA28877 X12451 CAA30981 Y18462 CAA77180 XM_005251716 XP_005251773 XM_011518263 XP_011516565 NM_001257971 NP_001244900 NM_001257972 NP_001244901 NM_001257973 NP_001244902 NM_001912 NP_001903 NM_145918 NP_666023 |
Function | Important for the overall degradation of proteins in lysosomes. |
Subcellular Location | Lysosome. |
Top Pathways | Lysosome, Phagosome, Rheumatoid arthritis, Proteoglycans in cancer, Antigen processing and presentation |
cathepsin L CRISPR/Cas9 KO Plasmid (h) - sc-400804 from Santa Cruz Biotechnology
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cathepsin L HDR Plasmid (h) - sc-400804-HDR from Santa Cruz Biotechnology
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cathepsin L Double Nickase Plasmid (h) - sc-400804-NIC from Santa Cruz Biotechnology
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cathepsin L Double Nickase Plasmid (h2) - sc-400804-NIC-2 from Santa Cruz Biotechnology
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cathepsin L CRISPR Activation Plasmid (h) - sc-400804-ACT from Santa Cruz Biotechnology
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cathepsin L CRISPR Activation Plasmid (h2) - sc-400804-ACT-2 from Santa Cruz Biotechnology
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cathepsin L Lentiviral Activation Particles (h) - sc-400804-LAC from Santa Cruz Biotechnology
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cathepsin L Lentiviral Activation Particles (h2) - sc-400804-LAC-2 from Santa Cruz Biotechnology
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cathepsin L siRNA (h) - sc-29938 from Santa Cruz Biotechnology
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cathepsin L shRNA Plasmid (h) - sc-29938-SH from Santa Cruz Biotechnology
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cathepsin L shRNA (h) Lentiviral Particles - sc-29938-V from Santa Cruz Biotechnology
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Cathepsin L RNAi - H00001514-R01 from Novus Biologicals
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Cathepsin L RNAi - H00001514-R02 from Novus Biologicals
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MISSION® esiRNA - EHU106791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2030 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2030 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03641 from Sigma-Aldrich
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CTSL siRNA (Human) - CRH1071 from Cohesion Biosciences
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CTSL - MBS8211888 from MyBioSource
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shRNA set against Human CTSL1 (NM_001912.4) - SHH271605 from Creative biogene
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Human CTSL siRNA - orb261573 from Biorbyt
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CTSL shRNA Plasmid (Human) - CHH1071 from Cohesion Biosciences
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CTSL1 miRNA 3'UTR clone - MiUTR3H-00376 from Creative biogene
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CTSL1 miRNA 3'UTR clone - MiUTR3H-00377 from Creative biogene
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