CTSL

Gene Symbol CTSL
Entrez Gene 1514
Alt Symbol CATL, CTSL1, MEP
Species Human
Gene Type protein-coding
Description cathepsin L
Other Description cathepsin L1|major excreted protein
Swissprots Q96QJ0 P07711 Q6IAV1
Accessions AAA66974 AAN87068 CAY55960 CAY55961 EAW62731 EAW62732 EAW62733 EAW62734 EAW62735 EAW62736 P07711 AF217997 AAG17239 AF304301 AAM89516 AF467444 AAQ05021 AK055599 AK075100 BAG52066 AL832167 AW270438 BC012612 AAH12612 BC142983 AAI42984 BI824449 BI829385 BM680778 BX537395 CAD97637 BX647101 BX647102 BX647413 BX647434 BX647435 BX648848 BX648849 BX649140 CB963086 CR457053 CAG33334 DN993009 DQ892930 ABM83856 DQ896179 ABM87178 X05256 CAA28877 X12451 CAA30981 Y18462 CAA77180 XM_005251716 XP_005251773 XM_011518263 XP_011516565 NM_001257971 NP_001244900 NM_001257972 NP_001244901 NM_001257973 NP_001244902 NM_001912 NP_001903 NM_145918 NP_666023
Function Important for the overall degradation of proteins in lysosomes.
Subcellular Location Lysosome.
Top Pathways Lysosome, Phagosome, Rheumatoid arthritis, Proteoglycans in cancer, Antigen processing and presentation

cathepsin L (33/2) - sc-32320 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
cathepsin L (33/2): sc-32320. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic and nuclear staining of cells in tubules.

cathepsin L (CPLH-2D4) - sc-32801 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Procathepsin L (CPLH-2D4): sc-32801. Western blot analysis of Procathepsin L expression in 32M1 whole cell lysate.

cathepsin L (C-18) - sc-6498 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cathepsin L (C-18): sc-6498. Western blot analysis of cathepsin L expression in rat kidney extract.

cathepsin L (H-80) - sc-10778 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
cathepsin L (H-80): sc-10778. Western blot analysis of cathepsin L expression in rat kidney tissue extract.

cathepsin L (S-20) - sc-6500 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cathepsin L (S-20): sc-6500. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver tissue (A) and immunofluorescence staining of methanol-fixed KNRK cells (B) showing cytoplasmic localization.

cathepsin L (22) - sc-135859 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
cathepsin L (22): sc-135859. Western blot analysis of cathepsin L expression in non-transfected: sc-110760 (A) and human cathepsin L transfected: sc-158353 (B) 293 whole cell lysates.

pan cathepsin (C-5) - sc-365614 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
pan cathepsin (C-5): sc-365614. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.

pan cathepsin (H-300) - sc-25537 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
pan cathepsin (H-300): sc-25537. Immunofluorescence staining of formalin-fixed HepG2 cells showing cytoplasmic localization.

Anti-Cathepsin L antibody - ab58991 from Abcam

Prices $388.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-Cathepsin L antibody (ab58991) at 1/500 dilution + Whole cell lysate prepared from human HCT116 cell at 10 µgSecondaryHRP-conjugated donkey ppolyclonal to rabbit IgG at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Cathepsin L antibody - ab203028 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Formalin-fixed, paraffin-embedded rat skin tissue labeling Cathepsin L with ab203028 at 1/200 dilution with DAB staining.

Anti-Cathepsin L antibody - ab103574 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cathepsin L antibody (ab103574) at 1/500 dilution + Mouse spleen tissue lysate at 50 µg

Anti-Cathepsin L antibody - ab95154 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cathepsin L antibody (ab95154) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 2 : HCT 116 (Human Colorectal Carcinoma) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Cathepsin L antibody - ab30445 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Cathepsin L antibody [33/2] - ab6314 from Abcam

Prices $401.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 33/2
IHC image of Cathepsin L staining in human colon adenocarcinoma formalin fixed paraffin embedded tissue section*, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab6314, 0.5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.*Tissue obtained from the Human Research Tissue Bank, supported by the NIHR Cambridge Biomedical Research Centre

Anti-Cathepsin L antibody [33/2] (HRP) - ab197278 from Abcam

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 33/2
All lanes : Anti-Cathepsin L antibody [33/2] (HRP) (ab197278) at 1/5000 dilutionLane 1 : Lung (Human) Tissue Lysate (ab4014)Lane 2 : Kidney (Human) Tissue Lysate - adult normal tissue (ab30203)Lysates/proteins at 20 µg per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-Cathepsin L antibody [CPL33/1] - ab62710 from Abcam

Prices $378.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone CPL33/1
Lane 1 :  Anti-Cathepsin L antibody [CPL33/1] (ab62710) at 1 µg/mlLane 2 :  Anti-Cathepsin L antibody [CPL33/1] (ab62710) at 0.5 µg/mlLane 3 :  Anti-Cathepsin L antibody [CPL33/1] (ab62710) at 0.25 µg/mlLane 4 :  Anti-Cathepsin L antibody [CPL33/1] (ab62710) at 0.12 µg/mlLane 5 :  Anti-Cathepsin L antibody [CPL33/1] (ab62710)Lane 1 : Equal amounts of total cell extract of A549 cells (ab7910)Lane 2 : Equal amounts of total cell extract of A549 cells (ab7910)Lane 3 : Equal amounts of total cell extract of A549 cells (ab7910)Lane 4 : Equal amounts of total cell extract of A549 cells (ab7910)Lane 5 : Equal amounts of total cell extract of A549 cells (ab7910) with CPL33/1 peptide

Anti-Cathepsin L antibody [EPR8011] - ab133641 from Abcam

Prices $398.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8011
All lanes : Anti-Cathepsin L antibody [EPR8011] (ab133641) at 1/1000 dilution (unpurified)Lane 1 : A549 cell lysateLane 2 : HCT-116 cell lysateLane 3 : NIH/3T3 cell lysateLane 4 : PC-12 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP-conjugated goat anti-rabbit IgG at 1/2000 dilution

Anti-Cathepsin L antibody - 2nd extracellular domain - ab49983 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cathepsin L antibody - 2nd extracellular domain (ab49983) at 1/1000 dilutionLane 1 : Sw1353 CM Serum FreeLane 2 : Sw1353 CM treated with TPA

Anti-Cathepsin L antibody - Catalytic domain - ab49984 from Abcam

Prices $382.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cathepsin L antibody - Catalytic domain (ab49984) at 1/1000 dilutionLane 1 : r-Human Cathepsin L at 0.04 µgLane 2 : r-Human Cathepsin L at 0.02 µgLane 3 : r-Human Cathepsin L at 0.01 µgLane 4 : r-Human Cathepsin L at 0.004 µgLane 5 : r-Human Cathepsin L at 0.002 µgLane 6 : r-Human Cathepsin V Lane 7 : r-Human Cathepsin V Lane 8 : r-Human Cathepsin V Lane 9 : r-Human Cathepsin V Lane 10 : r-Human Cathepsin V

Anti-Procathepsin L + Cathepsin L antibody - ab200738 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Procathepsin L + Cathepsin L antibody (ab200738)Lane 1 : HEK293T whole cell lysateLane 2 : sp2/0 whole cell lysateLane 3 : PC12 whole cell lysate

Anti-Procathepsin L + Cathepsin L antibody [CP-L14] - ab130005 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CP-L14

Anti-CTSL / Cathepsin L Antibody - LS-C35326 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CTSL / Cathepsin L Antibody - LS-C77988 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CTSL / Cathepsin L Antibody - LS-C85756 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTSL / Cathepsin L Antibody - LS-C144664 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
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