Gene Symbol | ZEB2 |
---|---|
Entrez Gene | 9839 |
Alt Symbol | HSPC082, SIP-1, SIP1, SMADIP1, ZFHX1B |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger E-box binding homeobox 2 |
Other Description | SMAD interacting protein 1|Smad-interacting protein 1|zinc finger E-box-binding homeobox 2|zinc finger homeobox 1b |
Swissprots | A0JP09 F5H814 B7Z2P2 Q9UED1 O60315 |
Accessions | AAK52081 AAX93269 AAX93276 EAX11575 EAX11576 EAX11577 O60315 AB011141 BAA25495 AB015341 BAA34798 AB056507 BAB40819 AB193095 BAD60927 AB193096 BAD60928 AF085983 AF161345 AAF28905 AI341193 AI858477 AK124806 AK294928 BAH11928 AK308124 AK308445 AL118674 BC025696 BC025730 BC035706 BC037975 BC060819 BC070275 BC127101 AAI27102 BC127102 AAI27103 BP218652 BU688017 DA305985 XM_006712881 XP_006712944 XM_006712882 XP_006712945 XM_011512231 XP_011510533 XM_011512232 XP_011510534 NM_001171653 NP_001165124 NM_014795 NP_055610 NR_033258 |
Function | Transcriptional inhibitor that binds to DNA sequence 5'- CACCT-3' in different promoters. Represses transcription of E- cadherin. {ECO:0000269|PubMed:16061479}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16061479, ECO:0000269|PubMed:9853615}. |
Top Pathways | MicroRNAs in cancer |
ZEB2 CRISPR/Cas9 KO Plasmid (h) - sc-400655 from Santa Cruz Biotechnology
|
||||||||
ZEB2 HDR Plasmid (h) - sc-400655-HDR from Santa Cruz Biotechnology
|
||||||||
ZEB2 Double Nickase Plasmid (h) - sc-400655-NIC from Santa Cruz Biotechnology
|
||||||||
ZEB2 Double Nickase Plasmid (h2) - sc-400655-NIC-2 from Santa Cruz Biotechnology
|
||||||||
SIP1 CRISPR Activation Plasmid (h) - sc-400655-ACT from Santa Cruz Biotechnology
|
||||||||
ZEB2 CRISPR Activation Plasmid (h2) - sc-400655-ACT-2 from Santa Cruz Biotechnology
|
||||||||
ZEB2 Lentiviral Activation Particles (h) - sc-400655-LAC from Santa Cruz Biotechnology
|
||||||||
ZEB2 Lentiviral Activation Particles (h2) - sc-400655-LAC-2 from Santa Cruz Biotechnology
|
||||||||
ZEB2 siRNA (h) - sc-38641 from Santa Cruz Biotechnology
|
||||||||
ZEB2 shRNA Plasmid (h) - sc-38641-SH from Santa Cruz Biotechnology
|
||||||||
ZEB2 shRNA (h) Lentiviral Particles - sc-38641-V from Santa Cruz Biotechnology
|
||||||||
ZEB2 RNAi - H00009839-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU010131 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN23158 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23158 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR09222 from Sigma-Aldrich
|
||||||||
ZEB2 siRNA (Human) - CRH6591 from Cohesion Biosciences
|
||||||||
ZEB2 - MBS8230569 from MyBioSource
|
||||||||
ZEB2 CRISPR/Cas9 KO Plasmid (h2) - sc-400655-KO-2 from Santa Cruz Biotechnology
|
||||||||
ZEB2 HDR Plasmid (h2) - sc-400655-HDR-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human ZEB2(NM_001171653.1) - SHR225924 from Creative biogene
|
||||||||
ZEB2 shRNA Plasmid (Human) - CHH6591 from Cohesion Biosciences
|
||||||||
ZEB2 miRNA 3'UTR clone - MiUTR1H-11423 from Creative biogene
|
||||||||
ZEB2 miRNA 3'UTR clone - MiUTR4H-TG10052 from Creative biogene
|