Gene Symbol | ZEB2 |
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Entrez Gene | 9839 |
Alt Symbol | HSPC082, SIP-1, SIP1, SMADIP1, ZFHX1B |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger E-box binding homeobox 2 |
Other Description | SMAD interacting protein 1|Smad-interacting protein 1|zinc finger E-box-binding homeobox 2|zinc finger homeobox 1b |
Swissprots | A0JP09 F5H814 B7Z2P2 Q9UED1 O60315 |
Accessions | AAK52081 AAX93269 AAX93276 EAX11575 EAX11576 EAX11577 O60315 AB011141 BAA25495 AB015341 BAA34798 AB056507 BAB40819 AB193095 BAD60927 AB193096 BAD60928 AF085983 AF161345 AAF28905 AI341193 AI858477 AK124806 AK294928 BAH11928 AK308124 AK308445 AL118674 BC025696 BC025730 BC035706 BC037975 BC060819 BC070275 BC127101 AAI27102 BC127102 AAI27103 BP218652 BU688017 DA305985 XM_006712881 XP_006712944 XM_006712882 XP_006712945 XM_011512231 XP_011510533 XM_011512232 XP_011510534 NM_001171653 NP_001165124 NM_014795 NP_055610 NR_033258 |
Function | Transcriptional inhibitor that binds to DNA sequence 5'- CACCT-3' in different promoters. Represses transcription of E- cadherin. {ECO:0000269|PubMed:16061479}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16061479, ECO:0000269|PubMed:9853615}. |
Top Pathways | MicroRNAs in cancer |
ZEB2 (E-11) - sc-271984 from Santa Cruz Biotechnology
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ZEB2 (H-260) - sc-48789 from Santa Cruz Biotechnology
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ZEB2 (L-20) - sc-18392 from Santa Cruz Biotechnology
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Anti-Smad Interacting Protein 1 antibody - ab25837 from Abcam
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Anti-Smad Interacting Protein 1 antibody - ab113655 from Abcam
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Anti-Smad Interacting Protein 1 antibody - C-terminal - ab170759 from Abcam
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Anti-Smad Interacting Protein 1 antibody - C-terminal - ab191364 from Abcam
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Anti-Smad Interacting Protein 1 antibody - N-terminal - ab135072 from Abcam
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Anti-ZEB2 / SIP-1 Antibody (C-Terminus) IHC-plus⢠- LS-B5294 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa1-350, clone 1E12) - LS-C336472 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (C-Terminus) IHC-plus⢠- LS-B5644 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa36-85) IHC-plus⢠- LS-B6533 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa1-200) - LS-C344085 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa1078-1105, AP) - LS-C218486 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa1078-1105, APC) - LS-C218487 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa1078-1105, FITC) - LS-C218488 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa1078-1105, Biotin) - LS-C218489 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa1078-1105, Azide-free, HRP) - LS-C218490 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa1078-1105, PE) - LS-C218492 from LifeSpan Bioscience
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Anti-ZEB2 Antibody (aa52-101) - LS-C292220 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa1078-1105) - LS-C160768 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa1085-1113) - LS-C326485 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa71-120) IHC-plus⢠- LS-B5497 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa948-962) - LS-C313494 from LifeSpan Bioscience
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Anti-ZEB2 / SIP-1 Antibody (aa521-534) IHC-plus⢠- LS-B7316 from LifeSpan Bioscience
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