Gene Symbol |
Usp46
|
Entrez Gene |
69727
|
Alt Symbol |
1190009E20Rik, 2410018I08Rik, AI451644
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
ubiquitin specific peptidase 46
|
Other Description |
deubiquitinating enzyme 46|ubiquitin carboxyl-terminal hydrolase 46|ubiquitin specific protease 46|ubiquitin thioesterase 46|ubiquitin thiolesterase 46|ubiquitin-specific-processing protease 46
|
Swissprots |
Q9H7U4 Q9H9T8 Q3ULU5 Q80V95 P62069
|
Accessions |
EDL37865 EDL37866 P62069 AK004525 AK010546 AK029604 AK039074 AK145298 BAE26353 BC030888 BC039916 AAH39916 XM_006504268 XP_006504331 XM_006504269 XP_006504332 NM_177561 NP_808229
|
Function |
Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2. {ECO:0000269|PubMed:19465912}.
|