Gene Symbol | Usp46 |
---|---|
Entrez Gene | 69727 |
Alt Symbol | 1190009E20Rik, 2410018I08Rik, AI451644 |
Species | Mouse |
Gene Type | protein-coding |
Description | ubiquitin specific peptidase 46 |
Other Description | deubiquitinating enzyme 46|ubiquitin carboxyl-terminal hydrolase 46|ubiquitin specific protease 46|ubiquitin thioesterase 46|ubiquitin thiolesterase 46|ubiquitin-specific-processing protease 46 |
Swissprots | Q9H7U4 Q9H9T8 Q3ULU5 Q80V95 P62069 |
Accessions | EDL37865 EDL37866 P62069 AK004525 AK010546 AK029604 AK039074 AK145298 BAE26353 BC030888 BC039916 AAH39916 XM_006504268 XP_006504331 XM_006504269 XP_006504332 NM_177561 NP_808229 |
Function | Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2. {ECO:0000269|PubMed:19465912}. |