| Gene Symbol | NNMT |
|---|---|
| Entrez Gene | 4837 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | nicotinamide N-methyltransferase |
| Other Description | - |
| Swissprots | P40261 |
| Accessions | AAA93158 ACA06031 CAM12693 CDH92517 EAW67243 EAW67244 P40261 AA402535 AK026845 BC000234 AAH00234 BI255889 CR541907 CAG46705 DQ892841 ABM83767 DQ896088 ABM87087 U08021 AAA19904 NM_006169 NP_006160 |
| Function | Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. |
| Subcellular Location | Cytoplasm. |
| Tissue Specificity | Predominantly expressed in the liver. A lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. Not detected in the brain or pancreas. |
| Top Pathways | Nicotinate and nicotinamide metabolism |