| Gene Symbol |
NNMT
|
| Entrez Gene |
4837
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nicotinamide N-methyltransferase
|
| Other Description |
-
|
| Swissprots |
P40261
|
| Accessions |
AAA93158 ACA06031 CAM12693 CDH92517 EAW67243 EAW67244 P40261 AA402535 AK026845 BC000234 AAH00234 BI255889 CR541907 CAG46705 DQ892841 ABM83767 DQ896088 ABM87087 U08021 AAA19904 NM_006169 NP_006160
|
| Function |
Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Predominantly expressed in the liver. A lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. Not detected in the brain or pancreas.
|
| Top Pathways |
Nicotinate and nicotinamide metabolism
|