Gene Symbol | NNMT |
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Entrez Gene | 4837 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | nicotinamide N-methyltransferase |
Other Description | - |
Swissprots | P40261 |
Accessions | AAA93158 ACA06031 CAM12693 CDH92517 EAW67243 EAW67244 P40261 AA402535 AK026845 BC000234 AAH00234 BI255889 CR541907 CAG46705 DQ892841 ABM83767 DQ896088 ABM87087 U08021 AAA19904 NM_006169 NP_006160 |
Function | Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Predominantly expressed in the liver. A lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. Not detected in the brain or pancreas. |
Top Pathways | Nicotinate and nicotinamide metabolism |
NNMT CRISPR/Cas9 KO Plasmid (h) - sc-403192 from Santa Cruz Biotechnology
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NNMT HDR Plasmid (h) - sc-403192-HDR from Santa Cruz Biotechnology
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NNMT Double Nickase Plasmid (h) - sc-403192-NIC from Santa Cruz Biotechnology
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NNMT Double Nickase Plasmid (h2) - sc-403192-NIC-2 from Santa Cruz Biotechnology
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NNMT CRISPR Activation Plasmid (h) - sc-403192-ACT from Santa Cruz Biotechnology
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NNMT CRISPR Activation Plasmid (h2) - sc-403192-ACT-2 from Santa Cruz Biotechnology
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NNMT Lentiviral Activation Particles (h) - sc-403192-LAC from Santa Cruz Biotechnology
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NNMT Lentiviral Activation Particles (h2) - sc-403192-LAC-2 from Santa Cruz Biotechnology
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NNMT siRNA (h) - sc-61213 from Santa Cruz Biotechnology
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NNMT shRNA Plasmid (h) - sc-61213-SH from Santa Cruz Biotechnology
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NNMT shRNA (h) Lentiviral Particles - sc-61213-V from Santa Cruz Biotechnology
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Nicotinamide N-Methyltransferase/NNMT RNAi - H00004837-R01 from Novus Biologicals
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MISSION® esiRNA - EHU054291 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15386 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15386 from Sigma-Aldrich
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NNMT siRNA (Human) - CRH3213 from Cohesion Biosciences
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shRNA set against Human NNMT (NM_006169.2) - SHH353357 from Creative biogene
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shRNA set against Human NNMT(NM_006169.2) - SHR014754 from Creative biogene
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NNMT shRNA Plasmid (Human) - CHH3213 from Cohesion Biosciences
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NNMT miRNA 3'UTR clone - MiUTR1H-06826 from Creative biogene
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