AKIP1

Gene Symbol AKIP1
Entrez Gene 56672
Alt Symbol BCA3, C11orf17
Species Human
Gene Type protein-coding
Description A kinase (PRKA) interacting protein 1
Other Description A-kinase-interacting protein 1|breast cancer associated gene 3|koyt binding protein 1|koyt binding protein 2|koyt binding protein 3|proline-rich protein BCA3
Swissprots Q8TAC6 Q8TAE0 Q8TAD3 Q8NBS2 Q9NQ31
Accessions AAM12865 AAM12866 AAM12867 CAB92290 CAF86919 EAW68614 EAW68615 EAW68616 Q9NQ31 AF493783 AAM12862 AF493784 AAM12863 AF493785 AAM12864 AF512007 AAM34785 AK075308 BAC11537 AK294506 BAG57722 AK294549 BAG57753 AW340643 BC030996 AAH30996 BM706322 BP355293 DB570956 HQ447743 ADQ32228 XM_006718264 XP_006718327 NM_001206646 NP_001193575 NM_001206647 NP_001193576 NM_001206648 NP_001193577 NM_020642 NP_065693 NR_045417 NR_045418 NM_001206645 NM_182901
Function Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. {ECO:0000269|PubMed:18178962, ECO:0000269|PubMed:20562110}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15630084, ECO:0000269|PubMed:18178962}. Note=Locates to punctate spots.
Tissue Specificity Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up- regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain. {ECO:0000269|PubMed:12527432, ECO:0000269|PubMed:15630084}.

BCA3 (N-12) - sc-133302 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-C11orf17 antibody - ab107196 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-C11orf17 antibody (ab107196) at 1/100 dilutionLane 1 : NCI-H292 cell line lysateLane 2 : CHO cell line lysateLane 3 : Mouse bladder tissue lysateLysates/proteins at 35 µg per lane.

Anti-C11orf17 antibody - ab135996 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-C11orf17 antibody (ab135996) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-C11orf17 antibody - ab69697 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-C11orf17 antibody (ab69697) at 1/500 dilutionLane 1 : C11orf17 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-AKIP1 / BCA3 Antibody (aa54-83, APC) - LS-C252415 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKIP1 / BCA3 Antibody (aa54-83, AP) - LS-C252414 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKIP1 / BCA3 Antibody (aa54-83, Azide-free, HRP) - LS-C252419 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKIP1 / BCA3 Antibody (aa54-83, FITC) - LS-C252418 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKIP1 / BCA3 Antibody - LS-C306177 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-AKIP1 / BCA3 Antibody (aa111-211) - LS-C306176 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-AKIP1 / BCA3 Antibody (aa54-83, PE) - LS-C252420 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKIP1 / BCA3 Antibody (aa54-83, Biotin) - LS-C252417 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKIP1 / BCA3 Antibody - LS-C309386 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AKIP1 / BCA3 Antibody (aa111-160) - LS-C119278 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human heart tissue, using BCA3 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-AKIP1 / BCA3 Antibody (aa61-91) - LS-C319788 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKIP1 / BCA3 Antibody - LS-C309384 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AKIP1 / BCA3 Antibody (aa85-134) - LS-C200178 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using BCA3 antibody.

Anti-AKIP1 / BCA3 Antibody (aa54-83) - LS-C156754 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BCA3 Antibody western blot of mouse bladder tissue lysates (35 ug/lane). The BCA3 antibody detected the BCA3 protein (arrow).

BCA3 Antibody - NBP1-68161 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: BCA3 Antibody [NBP1-68161] - Analysis of extracts from Jurkat cells, using BCA3 Antibody. The lane on the right is treated with the synthesized peptide.

BCA3 Antibody - H00056672-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: BCA3 Antibody [H00056672-B01P] - Analysis of C11orf17 expression in transfected 293T cell line by C11orf17 polyclonal antibody. Lane 1: C11orf17 transfected lysate(23.1 KDa). Lane 2: Non-transfected lysate.

BCA3 Antibody - H00056672-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: BCA3 Antibody [H00056672-D01P] - Analysis of C11orf17 expression in transfected 293T cell line by C11orf17 polyclonal antibody.Lane 1: C11orf17 transfected lysate(23.10 KDa).Lane 2: Non-transfected lysate.

Monoclonal Anti-C11ORF17, (C-terminal) antibody produced in mouse - SAB1403314 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B11
<B>Immunoblotting</B><BR/>Monoclonal Anti-C11orf17: <B>Cat. No. SAB1403314</B>: Antibody concentration: 1 μg/mL. Specific band of ~37.1 kDa using immunogen protein lysate.

Anti-C11orf17 (156-170) antibody produced in rabbit - SAB1102559 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human C11orf17 was separated on SDS-PAGE, blotted with Anti-C11orf17 (156-170) (<B>Cat. No. SAB1102559</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500 <BR/>2. Antibody dilution 1:500 + C11orf17 immunizing peptide (human, 156-170)

Anti-C11orf17 (111-125) antibody produced in rabbit - SAB1102558 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human FLAG<SUP>®</SUP>-C11orf17 fusion protein was separated on SDS-PAGE, blotted with Anti-C11orf17 (111-125) (<B>Cat. No. SAB1102558</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500 <BR/>2. Antibody dilution 1:500 + C11orf17 immunizing peptide (human, 111-125) <BR/>3. Negative control (only secondary antibody)<BR/>4. Anti-FLAG<SUP>®</SUP> antibody (<B>Cat. No. F7425</B>), working concentration 2 μg/mL

Anti-BCA3 antibody produced in rabbit - SAB4502429 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BCA3: <B>Cat. No. SAB4502429</B>: Immunohistochemistry analysis of paraffin-embedded human heart tissue using Anti-BCA3 antibody. Cells on the left were treated with the Anti-BCA3 antibody. Cells on the right (negative control) were treated with both Anti-BCA3 antibody and the synthesized immunogen peptide.
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