Gene Symbol | IFT81 |
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Entrez Gene | 28981 |
Alt Symbol | CDV-1, CDV-1R, CDV1, CDV1R, DV1 |
Species | Human |
Gene Type | protein-coding |
Description | intraflagellar transport 81 |
Other Description | carnitine deficiency-associated gene expressed in ventricle 1|carnitine deficiency-associated protein expressed in ventricle 1|intraflagellar transport 81 homolog|intraflagellar transport protein 81 homolog |
Swissprots | Q8NB51 Q2YDY1 Q9BSV2 Q9UNY8 Q8WYA0 |
Accessions | EAW97897 EAW97898 EAW97899 EAW97900 EAW97901 Q8WYA0 AF078932 AAD48091 AF139540 AAP97269 AF250326 AAL50343 AF332010 AAO32947 AK000874 AK091549 BAC03690 AK291043 BAF83732 BC004536 AAH04536 BC005396 AAH05396 BC029349 AAH29349 BC108257 AAI08258 BP351086 HQ447321 ADQ31808 XM_011538232 XP_011536534 XM_011538233 XP_011536535 XM_011538234 XP_011536536 XR_429093 XR_944523 NM_001143779 NP_001137251 NM_014055 NP_054774 NM_031473 NP_113661 |
Function | Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis. {ECO:0000269|PubMed:23990561}. |
Subcellular Location | Cell projection, cilium {ECO:0000305|PubMed:23990561}. |
Tissue Specificity | Highly expressed in testis, moderately in ovary, heart, liver, skeletal muscle, kidney and pancreas, low in prostate, brain, placenta and lung and not detected in spleen, thymus, small intestine and colon. Isoform CDV-1R is abundantly expressed in testis. {ECO:0000269|PubMed:12549821}. |
IFT81 CRISPR/Cas9 KO Plasmid (h) - sc-408865 from Santa Cruz Biotechnology
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IFT81 HDR Plasmid (h) - sc-408865-HDR from Santa Cruz Biotechnology
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IFT81 Double Nickase Plasmid (h) - sc-408865-NIC from Santa Cruz Biotechnology
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IFT81 Double Nickase Plasmid (h2) - sc-408865-NIC-2 from Santa Cruz Biotechnology
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IFT81 CRISPR Activation Plasmid (h) - sc-408865-ACT from Santa Cruz Biotechnology
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IFT81 CRISPR Activation Plasmid (h2) - sc-408865-ACT-2 from Santa Cruz Biotechnology
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IFT81 Lentiviral Activation Particles (h) - sc-408865-LAC from Santa Cruz Biotechnology
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IFT81 Lentiviral Activation Particles (h2) - sc-408865-LAC-2 from Santa Cruz Biotechnology
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IFT81 siRNA (h) - sc-96191 from Santa Cruz Biotechnology
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IFT81 shRNA Plasmid (h) - sc-96191-SH from Santa Cruz Biotechnology
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IFT81 shRNA (h) Lentiviral Particles - sc-96191-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU098611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10509 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10509 from Sigma-Aldrich
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IFT81 siRNA (Human) - CRH9144 from Cohesion Biosciences
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IFT81 - MBS8200479 from MyBioSource
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shRNA set against Human IFT81 (NM_014055.3) - SHH317365 from Creative biogene
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Human IFT81 siRNA - orb269646 from Biorbyt
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IFT81 shRNA Plasmid (Human) - CHH9144 from Cohesion Biosciences
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IFT81 miRNA 3'UTR clone - MiUTR3H-07725 from Creative biogene
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IFT81 miRNA 3'UTR clone - MiUTR3H-07726 from Creative biogene
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IFT81 miRNA 3'UTR clone - MiUTR3H-07727 from Creative biogene
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