BBS5

Gene Symbol	BBS5
Entrez Gene	129880
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	Bardet-Biedl syndrome 5
Other Description	Bardet-Biedl syndrome 5 protein
Swissprots	Q8N3I7 D3DPC3 Q6PKN0
Accessions	AAY24116 CAK32417 EAX11276 EAX11277 EAX11278 EAX11279 Q8N3I7 AA043704 AK097935 AK312680 AL834305 CAD38975 AM393220 CAL38098 AY604003 AAT08182 AY604004 AAT08183 BC044593 AAH44593 BP311042 CA336791 CD245392 H09195 NM_152384 NP_689597
Function	The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly. {ECO:0000269|PubMed:17574030, ECO:0000269|Pub
Subcellular Location	Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Note=Localizes to basal bodies. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BBS5 full length protein - ab165320 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BBS5 Antibody Blocking Peptide - LS-E19081 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BBS5 Antibody Blocking Peptide - LS-E19082 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BBS5 Protein - H00129880-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

BBS5 Blocking Peptide - 33R-9497 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BBS5 Blocking Peptide - 33R-6522 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BBS5 - H00129880-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

BBS5 - H00129880-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

BBS5 fusion protein - Ag6844 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

BBS5 fusion protein - ag6153 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Bardet-Biedl syndrome 5 protein(BBS5) - CSB-YP847625HU CSB-EP847625HU CSB-BP847625HU CSB-MP847625HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BBS5-Blocking-Peptide-Center - BP20560a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BBS5 Peptide, Human - M34GP01345H from Creative Peptides Category Peptide Source Synthetic. Species Human

BBS5 Antibody - SH-A10554 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

Bardet-Biedl syndrome 5 protein (BBS5), Recombinant Protein - MBS1454260 from MyBioSource Category Protein Prices $1,105.00, $1,105.00, $1,335.00, $1,335.00, $1,745.00, $1,745.00, $2,210.00, $2,210.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human BBS5 Protein, GST-tagged - BBS5-109H from Creative Biomart Category Protein Source Wheat Germ Species Human

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