BBS5

Gene Symbol BBS5
Entrez Gene 129880
Alt Symbol -
Species Human
Gene Type protein-coding
Description Bardet-Biedl syndrome 5
Other Description Bardet-Biedl syndrome 5 protein
Swissprots Q8N3I7 D3DPC3 Q6PKN0
Accessions AAY24116 CAK32417 EAX11276 EAX11277 EAX11278 EAX11279 Q8N3I7 AA043704 AK097935 AK312680 AL834305 CAD38975 AM393220 CAL38098 AY604003 AAT08182 AY604004 AAT08183 BC044593 AAH44593 BP311042 CA336791 CD245392 H09195 NM_152384 NP_689597
Function The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly. {ECO:0000269|PubMed:17574030, ECO:0000269|Pub
Subcellular Location Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Note=Localizes to basal bodies. {ECO:0000250}.

BBS5 (T-18) - sc-51468 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BBS5 (T-18): sc-51468. Western blot analysis of BBS5 expression in LADMAC whole cell lysate (A) and mouse heart tissue extract (B).

BBS5 (Y-15) - sc-51469 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BBS5 (T-15): sc-51469. Western blot analysis of BBS5 expression in mouse liver tissue extract.

Anti-BBS5 antibody - ab203621 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed and paraffin embedded rat liver labeling BBS5 with ab203621 at 1/200 followed by conjugation to the secondary antibody and DAB staining

Anti-BBS5 antibody - ab85433 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BBS5 antibody (ab85433) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-BBS5 antibody - ab67162 from Abcam

Prices $359.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-BBS5 antibody (ab67162) at 1/500 dilutionLane 1 : Transfected 293T cell lysateLane 2 : non Transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

Anti-BBS5 Antibody - LS-C306509 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-BBS5 Antibody (C-Terminus) - LS-C102493 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BBS5 antibody LS-C102493 Western blot of 293T cell lysate.

Anti-BBS5 Antibody (N-Terminus) - LS-C135010 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BBS5 antibody LS-C135010 Western blot of COLO205 cell lysate.

Anti-BBS5 Antibody (aa108-141) - LS-C344202 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from K562 cell line with BBS5 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.

BBS5 Antibody - NBP1-55191 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BBS5 Antibody [NBP1-55191] - Titration: 0.2-1 ug/ml, Positive Control: 293T cell lysate.

BBS5 Antibody - H00129880-B01P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of BBS5 expression in transfected 293T cell line by BBS5 MaxPab polyclonal antibody. Lane 1: BBS5 transfected lysate (37.51 KDa). Lane 2: Non-transfected lysate.

BBS5 Polyclonal Antibody - bs-9438R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-BBS5 Polyclonal Antibody, Unconjugated (bs-9438R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-BBS5 antibody produced in rabbit - HPA036416 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BBS5: <B>Cat. No. HPA036416</B>: Immunohistochemical staining of human stomach shows moderate cytoplasmic and membrane positivity in glandular cells.

Anti-BBS5 antibody produced in mouse - SAB1408306 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-BBS5: <B>Cat. No. SAB1408306</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~37.5 kDa using BBS5 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

BBS5 antibody - N-terminal region (ARP52930_P050) - ARP52930_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BBS5 antibody - middle region (ARP52931_P050) - ARP52931_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BBS5-Antibody-Center - AP20560a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysate from K562 cell line, using BBS5 Antibody (Center)(Cat. #AP20560a). AP20560a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.

BBS5-Antibody-Center - AW5288 from Abgent, a WuXi AppTec company

Prices $110.00, $325.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from K562,PC-3 cell line (from left to right), using BBS5 Antibody (Center)(Cat. #AW5288). AW5288 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.

BBS5 antibody, Internal - GTX45664 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-BBS5 antibody, Internal used in Western blot. GTX45664

Anti -BBS5 (Bardet-Biedl Syndrome 5 Protein, DKFZp762I194) - 123853 from USBiological Life Science

Host Mouse
Clonality Polyclonal

BBS5 Antibody - middle region (OAAB18082) - OAAB18082 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

BBS5 Antibody (OABF01894) - OABF01894 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BBS5 antibody - 70R-9214 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

BBS5 antibody - 70R-2989 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

BBS5 antibody - 14569-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human stomach tissue slide using 14569-1-AP( BBS5 Antibody) at dilution of 1:50 (under 10x lens)
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