| Gene Symbol |
RPRM
|
| Entrez Gene |
56475
|
| Alt Symbol |
REPRIMO
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
reprimo, TP53 dependent G2 arrest mediator candidate
|
| Other Description |
candidate mediator of the p53 dependent G2 arrest|candidate mediator of the p53-dependent G2 arrest|protein reprimo|reprimo, TP53 dependant G2 arrest mediator candidate
|
| Swissprots |
Q9NS64 B2R4V1
|
| Accessions |
AAY14783 CAF85975 EAX11467 Q9NS64 AA452090 AB043585 BAB01513 AK074808 BAG52007 AK311958 BAG34898 BC002908 AAH02908 HQ448350 ADQ32830 NM_019845 NP_062819
|
| Function |
May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
| Top Pathways |
p53 signaling pathway
|