Gene Symbol | RPRM |
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Entrez Gene | 56475 |
Alt Symbol | REPRIMO |
Species | Human |
Gene Type | protein-coding |
Description | reprimo, TP53 dependent G2 arrest mediator candidate |
Other Description | candidate mediator of the p53 dependent G2 arrest|candidate mediator of the p53-dependent G2 arrest|protein reprimo|reprimo, TP53 dependant G2 arrest mediator candidate |
Swissprots | Q9NS64 B2R4V1 |
Accessions | AAY14783 CAF85975 EAX11467 Q9NS64 AA452090 AB043585 BAB01513 AK074808 BAG52007 AK311958 BAG34898 BC002908 AAH02908 HQ448350 ADQ32830 NM_019845 NP_062819 |
Function | May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Top Pathways | p53 signaling pathway |
Reprimo CRISPR/Cas9 KO Plasmid (h) - sc-405388 from Santa Cruz Biotechnology
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Reprimo HDR Plasmid (h) - sc-405388-HDR from Santa Cruz Biotechnology
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Reprimo Double Nickase Plasmid (h) - sc-405388-NIC from Santa Cruz Biotechnology
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Reprimo Double Nickase Plasmid (h2) - sc-405388-NIC-2 from Santa Cruz Biotechnology
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Reprimo CRISPR Activation Plasmid (h) - sc-405388-ACT from Santa Cruz Biotechnology
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Reprimo CRISPR Activation Plasmid (h2) - sc-405388-ACT-2 from Santa Cruz Biotechnology
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Reprimo Lentiviral Activation Particles (h) - sc-405388-LAC from Santa Cruz Biotechnology
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Reprimo Lentiviral Activation Particles (h2) - sc-405388-LAC-2 from Santa Cruz Biotechnology
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Reprimo siRNA (h) - sc-94986 from Santa Cruz Biotechnology
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Reprimo shRNA Plasmid (h) - sc-94986-SH from Santa Cruz Biotechnology
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Reprimo shRNA (h) Lentiviral Particles - sc-94986-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU103361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18616 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18616 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12384 from Sigma-Aldrich
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RPRM siRNA (Human) - CRJ1142 from Cohesion Biosciences
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RPRM - MBS8210371 from MyBioSource
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Human RPRM siRNA - orb271643 from Biorbyt
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RPRM shRNA Plasmid (Human) - CHJ1142 from Cohesion Biosciences
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