Gene Symbol |
POU1F1
|
Entrez Gene |
5449
|
Alt Symbol |
CPHD1, GHF-1, PIT1, POU1F1a, Pit-1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
POU class 1 homeobox 1
|
Other Description |
POU domain, class 1, transcription factor 1|growth hormone factor 1|pituitary-specific positive transcription factor 1
|
Swissprots |
Q15133 O75757 P28069 Q15132 Q9UEL3 Q9UD34
|
Accessions |
BAA02291 BAA34536 CAA54441 EAW68866 EAW68867 P28069 BC152851 AAI52852 D10216 BAA01068 L18781 AAA60093 S73501 AAB31227 X62429 CAA44295 X72215 CAA51017 NM_000306 NP_000297 NM_001122757 NP_001116229
|
Function |
Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'- TAAAT-3'.
|
Subcellular Location |
Nucleus.
|