Gene Symbol | POU1F1 |
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Entrez Gene | 5449 |
Alt Symbol | CPHD1, GHF-1, PIT1, POU1F1a, Pit-1 |
Species | Human |
Gene Type | protein-coding |
Description | POU class 1 homeobox 1 |
Other Description | POU domain, class 1, transcription factor 1|growth hormone factor 1|pituitary-specific positive transcription factor 1 |
Swissprots | Q15133 O75757 P28069 Q15132 Q9UEL3 Q9UD34 |
Accessions | BAA02291 BAA34536 CAA54441 EAW68866 EAW68867 P28069 BC152851 AAI52852 D10216 BAA01068 L18781 AAA60093 S73501 AAB31227 X62429 CAA44295 X72215 CAA51017 NM_000306 NP_000297 NM_001122757 NP_001116229 |
Function | Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'- TAAAT-3'. |
Subcellular Location | Nucleus. |
Pit-1 CRISPR/Cas9 KO Plasmid (h) - sc-401671 from Santa Cruz Biotechnology
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Pit-1 HDR Plasmid (h) - sc-401671-HDR from Santa Cruz Biotechnology
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Pit-1 Double Nickase Plasmid (h) - sc-401671-NIC from Santa Cruz Biotechnology
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Pit-1 Double Nickase Plasmid (h2) - sc-401671-NIC-2 from Santa Cruz Biotechnology
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Pit-1 CRISPR Activation Plasmid (h) - sc-401671-ACT from Santa Cruz Biotechnology
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Pit-1 CRISPR Activation Plasmid (h2) - sc-401671-ACT-2 from Santa Cruz Biotechnology
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Pit-1 Lentiviral Activation Particles (h) - sc-401671-LAC from Santa Cruz Biotechnology
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Pit-1 Lentiviral Activation Particles (h2) - sc-401671-LAC-2 from Santa Cruz Biotechnology
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Pit-1 siRNA (h) - sc-36234 from Santa Cruz Biotechnology
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Pit-1 shRNA Plasmid (h) - sc-36234-SH from Santa Cruz Biotechnology
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Pit-1 shRNA (h) Lentiviral Particles - sc-36234-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN17172 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17172 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01843 from Sigma-Aldrich
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POU1F1 siRNA (Human) - CRH3651 from Cohesion Biosciences
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Pit1 RNAi - H00005449-R01 from Novus Biologicals
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shRNA set against Human POU1F1 (NM_000306.2) - SHH380004 from Creative biogene
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Human POU1F1 siRNA - orb264153 from Biorbyt
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POU1F1 shRNA Plasmid (Human) - CHH3651 from Cohesion Biosciences
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POU1F1 miRNA 3'UTR clone - MiUTR4H-TG06899 from Creative biogene
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