| Gene Symbol |
AKAP8L
|
| Entrez Gene |
26993
|
| Alt Symbol |
HA95, HAP95, NAKAP, NAKAP95
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
A kinase (PRKA) anchor protein 8-like
|
| Other Description |
A-kinase anchor protein 8-like|AKAP8-like protein|helicase A-binding protein 95 kDa|homologous to AKAP95 protein|neighbor of A-kinase anchoring protein 95|neighbor of AKAP95
|
| Swissprots |
Q9UGM0 Q96J58 Q9ULX6 B4DJ74 Q9NRQ0 O94792 B5BU90
|
| Accessions |
EAW84475 EAW84476 EAW84477 EAW84478 Q9ULX6 AB015332 BAA34791 AB025905 BAA85003 AB451326 BAG70140 AB451469 BAG70283 AF199414 AAF86048 AJ243467 CAB65092 AK001594 BAG50946 AK094736 AK225046 AK225291 AK295956 BAG58736 AK310990 AL133576 CAB63723 BC000713 AAH00713 BF973758 BI458860 BM726437 BQ006924 BQ185989 BU740636 CD244113 CD672169 DA315789 DB099586 DQ891853 ABM82779 DQ895043 ABM85969 XM_005259854 XP_005259911 XM_011527916 XP_011526218 XR_244065 XR_936170 NM_001291478 NP_001278407 NM_014371 NP_055186 NR_111971
|
| Function |
Could play a role in constitutive transport element (CTE)-mediated gene expression. Does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May regulate the initiation phase of DNA replication when associated with TMPO-beta.
|
| Subcellular Location |
Nucleus matrix. Cytoplasm. Note=Colocalizes with PRPF40A in the nuclear matrix (By similarity). Nuclear at steady state but shuttles between the nucleus and cytoplasm. Associated with the nuclear matrix. {ECO:0000250}.
|
| Tissue Specificity |
Expressed in the brain cortex (at protein level). {ECO:0000269|PubMed:16391387}.
|
| Top Pathways |
Epstein-Barr virus infection
|