AKAP8L

Gene Symbol AKAP8L
Entrez Gene 26993
Alt Symbol HA95, HAP95, NAKAP, NAKAP95
Species Human
Gene Type protein-coding
Description A kinase (PRKA) anchor protein 8-like
Other Description A-kinase anchor protein 8-like|AKAP8-like protein|helicase A-binding protein 95 kDa|homologous to AKAP95 protein|neighbor of A-kinase anchoring protein 95|neighbor of AKAP95
Swissprots Q9UGM0 Q96J58 Q9ULX6 B4DJ74 Q9NRQ0 O94792 B5BU90
Accessions EAW84475 EAW84476 EAW84477 EAW84478 Q9ULX6 AB015332 BAA34791 AB025905 BAA85003 AB451326 BAG70140 AB451469 BAG70283 AF199414 AAF86048 AJ243467 CAB65092 AK001594 BAG50946 AK094736 AK225046 AK225291 AK295956 BAG58736 AK310990 AL133576 CAB63723 BC000713 AAH00713 BF973758 BI458860 BM726437 BQ006924 BQ185989 BU740636 CD244113 CD672169 DA315789 DB099586 DQ891853 ABM82779 DQ895043 ABM85969 XM_005259854 XP_005259911 XM_011527916 XP_011526218 XR_244065 XR_936170 NM_001291478 NP_001278407 NM_014371 NP_055186 NR_111971
Function Could play a role in constitutive transport element (CTE)-mediated gene expression. Does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May regulate the initiation phase of DNA replication when associated with TMPO-beta.
Subcellular Location Nucleus matrix. Cytoplasm. Note=Colocalizes with PRPF40A in the nuclear matrix (By similarity). Nuclear at steady state but shuttles between the nucleus and cytoplasm. Associated with the nuclear matrix. {ECO:0000250}.
Tissue Specificity Expressed in the brain cortex (at protein level). {ECO:0000269|PubMed:16391387}.
Top Pathways Epstein-Barr virus infection

AKAP 8L (A-1) - sc-376630 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AKAP 8L (A-1): sc-376630. Western blot analysis of AKAP 8L expression in Jurkat whole cell lysate.

AKAP 8L (B-6) - sc-376338 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AKAP 8L (B-6): sc-376338. Western blot analysis of AKAP 8L expression in Jurkat whole cell lysate.

AKAP 8L (C-12) - sc-132213 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AKAP 8L (C-12): sc-132213. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

Anti-AKAP8L antibody - ab51342 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AKAP8L antibody (ab51342) at 1.25 µg/ml + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG (1:100,000)

Anti-AKAP8L antibody - ab184873 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human testis tissue labeling AKAP8L with ab184873 at 1/500 dilution.

Anti-AKAP8L antibody - ab85413 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab85413, at 1/100 dilution, staining AKAP8L in formalin-fixed, paraffin-embedded human breast carcinoma by Immunohistochemistry using a Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Hilyte PlusTM 555 secondary antibody at 1/100 dilution.

Anti-AKAP8L antibody - C-terminal - ab173206 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-AKAP8L antibody - C-terminal (ab173206) at 1/100 dilution + Mouse cerebellum tissue lysate at 35 µg

Anti-AKAP8L Antibody (aa485-512, AP) - LS-C251091 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKAP8L Antibody (aa485-512, APC) - LS-C251092 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKAP8L Antibody (aa351-400) - LS-C116959 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AKAP8L antibody LS-C116959 Western blot of Jurkat lysate.

Anti-AKAP8L Antibody (aa485-512, FITC) - LS-C251093 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKAP8L Antibody (aa485-512, Biotin) - LS-C251094 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKAP8L Antibody (aa531-580) - LS-C201246 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Esophagus Tumor. AKAP8L antibody dilution 1.0 ug/ml.

Anti-AKAP8L Antibody (aa485-512, Azide-free, HRP) - LS-C251095 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKAP8L Antibody (aa485-512, PE) - LS-C251096 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKAP8L Antibody (aa525-575) - LS-C286061 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AKAP8L Antibody (aa484-512) - LS-C319395 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AKAP8L Antibody (C-Terminus) - LS-C31359 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
AKAP8L antibody LS-C31359 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-AKAP8L Antibody - LS-C180195 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: HA95/AKAP8L Antibody - IHC of HA95/AKAP8L in human ovarian cancer using DAB with hematoxylin counterstain.

Anti-AKAP8L Antibody (aa485-512) - LS-C161026 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
AKAP8L Antibody western blot of mouse cerebellum tissue lysates (35 ug/lane). The AKAP8L antibody detected the AKAP8L protein (arrow).

Anti-AKAP8L Antibody (aa596-646) - LS-C286064 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human AKAP8L/HA95 by Immunohistochemistry. Sample: FFPE section of human lung carcinoma. Antibody: Affinity purified rabbit anti-AKAP8L/HA95 used at a dilution of 1:200 (1 ug/ml).

Anti-AKAP8L Antibody (aa596-646) - LS-C286523 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human AKAP8L/HA95 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-AKAP8L/HA95 used at a dilution of 1:250.

HA95/AKAP8L Antibody - NBP1-79140 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: HA95/AKAP8L Antibody [NBP1-79140] - HA95/AKAP8L antibody was tested in HeLa cells with DyLight 488 (green). Nuclei and alpha Tubulin (NB100-690) were counterstained with DAPI (blue) and DyLight 550 (red).

HA95/AKAP8L Antibody - NB100-61606 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HA95/AKAP8L Antibody [NB100-61606] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells.  NB100-61606 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. AKAP8L/HA95 was also immunoprecipitated by rabbit anti-AKAP8L/HA95 antibody NB100-61605, which recognizes an upstream epitope.

HA95/AKAP8L Antibody - NB100-61605 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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