OGDH

Gene Symbol	OGDH
Entrez Gene	4967
Alt Symbol	AKGDH, E1k, OGDC
Species	Human
Gene Type	protein-coding
Description	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Other Description	2-oxoglutarate dehydrogenase complex component E1|2-oxoglutarate dehydrogenase, mitochondrial|OGDC-E1|oxoglutarate decarboxylase|oxoglutarate dehydrogenase (succinyl-transferring)
Swissprots	Q9UDX0 D3DVL0 Q96DD3 E9PBM1 Q02218 B4E2U9
Accessions	AAQ96884 AAQ96885 BAA06836 EAW61086 EAW61087 EAW61088 EAW61089 Q02218 AI244565 AK293871 BAG57261 AK294951 BAG58026 AK296400 BAG59067 AK302805 BAG64007 AK304439 BAG65261 AK304690 BAG65461 AK314179 AU140451 BC004964 AAH04964 BC009580 AAH09580 BC014617 AAH14617 BC128549 AAI28550 BC128550 AAI28551 BM998792 BU682361 D10523 BAA01393 DC401267 DQ891880 ABM82806 DQ925673 ABL59900 DQ925674 ABL59901 EU176648 ABW03449 XM_005249759 XP_005249816 XM_005249761 XP_005249818 XM_011515408 XP_011513710 NM_001003941 NP_001003941 NM_001165036 NP_001158508 NM_002541 NP_002532
Function	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
Subcellular Location	Mitochondrion matrix.
Top Pathways	Citrate cycle (TCA cycle), Lysine degradation, Tryptophan metabolism, Carbon metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

α-KGD CRISPR/Cas9 KO Plasmid (h) - sc-402915 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

α-KGD HDR Plasmid (h) - sc-402915-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

α-KGD Double Nickase Plasmid (h) - sc-402915-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

α-KGD Double Nickase Plasmid (h2) - sc-402915-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

α-KGD CRISPR Activation Plasmid (h) - sc-402915-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

α-KGD CRISPR Activation Plasmid (h2) - sc-402915-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

α-KGD Lentiviral Activation Particles (h) - sc-402915-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

α-KGD Lentiviral Activation Particles (h2) - sc-402915-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

α-KGD siRNA (h) - sc-60105 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

α-KGD shRNA Plasmid (h) - sc-60105-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

α-KGD shRNA (h) Lentiviral Particles - sc-60105-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU102861 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® esiRNA - EHU155451 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU016791 from Sigma-Aldrich Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN15701 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15701 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08129 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr08129

OGDH siRNA (Human) - CRH3296 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human OGDH (NM_002541.3) - SHH357456 from Creative biogene Category siRNA Species Reactivities Human

Human OGDH siRNA - orb263798 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

OGDH shRNA Plasmid (Human) - CHH3296 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

OGDH miRNA 3'UTR clone - MiUTR3H-12729 from Creative biogene Species Reactivities Human

OGDH miRNA 3'UTR clone - MiUTR3H-12730 from Creative biogene Species Reactivities Human

OGDH miRNA 3'UTR clone - MiUTR3H-12731 from Creative biogene Species Reactivities Human

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