HAMP

Gene Symbol HAMP
Entrez Gene 57817
Alt Symbol HEPC, HFE2B, LEAP1, PLTR
Species Human
Gene Type protein-coding
Description hepcidin antimicrobial peptide
Other Description hepcidin|liver-expressed antimicrobial peptide 1|putative liver tumor regressor
Swissprots P81172 Q9BY68 Q1HE14
Accessions ABF47098 CAG29368 CAR82669 CAR82670 CAR82671 CAR82672 CAR82673 CAR82674 CAR82675 CAR82676 CAR82677 CAR82678 CAR82679 CAR82680 CAR82681 CAR82682 CAR82683 CAR82684 CAR82685 CAR82686 CAR82687 CAR82688 CAR82689 CAR82690 CAR82691 CAR82692 CAR82693 CAR82694 CAR82695 CAR82696 CAR82697 CAR82698 CAR82699 CAR82700 CAR82701 CAR82702 P81172 AF131292 AAK14912 AF147355 AF309489 AAG23966 AJ277280 CAC09419 AK096110 AY358669 AAQ89032 BC020612 AAH20612 NM_021175 NP_066998
Function Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005). {ECO:0000269|PubMed:22306005}.
Subcellular Location Secreted.
Tissue Specificity Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine. {ECO:0000269|PubMed:11034317}.

hepcidin CRISPR/Cas9 KO Plasmid (h) - sc-403222 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

hepcidin HDR Plasmid (h) - sc-403222-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

hepcidin Double Nickase Plasmid (h) - sc-403222-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

hepcidin Double Nickase Plasmid (h2) - sc-403222-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

hepcidin CRISPR Activation Plasmid (h) - sc-403222-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

hepcidin CRISPR Activation Plasmid (h2) - sc-403222-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

hepcidin Lentiviral Activation Particles (h) - sc-403222-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

hepcidin Lentiviral Activation Particles (h2) - sc-403222-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

hepcidin siRNA (h) - sc-97892 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

hepcidin shRNA Plasmid (h) - sc-97892-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

hepcidin shRNA (h) Lentiviral Particles - sc-97892-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU056081 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9861 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9861 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HAMP siRNA (Human) - CRJ1682 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Hepcidin Antimicrobial Peptide RNAi - H00057817-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

HAMP - MBS8238176 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

hepcidin CRISPR/Cas9 KO Plasmid (h2) - sc-403222-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

hepcidin HDR Plasmid (h2) - sc-403222-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human HAMP (NM_021175.2) - SHH310213 from Creative biogene

Category siRNA
Species Reactivities Human

Human HAMP siRNA - orb272183 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HAMP shRNA Plasmid (Human) - CHJ1682 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HAMP miRNA 3'UTR clone - MiUTR1H-04369 from Creative biogene

Species Reactivities Human
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